FlyBase Allele Report: Dmel\dpp[unspecified]

General Information

Symbol

Dmel\dpp^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0057601

Feature type

allele

Associated gene

Dmel\dpp

Associated Insertion(s)

Carried in Construct

Also Known As

dpp^hin, unspecified

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Dworkin and Gibson, 2006)

Phenotype Manifest In

embryonic hindgut

(Iwaki and Lengyel, 2002)

genital disc primordium

(Chen et al., 2005)

germline cell | male

(Schulz et al., 2004)

hub cell

(Schulz et al., 2004)

Detailed Description

Statement

Reference

Stage 15 dpp^unspecified embryos have 30-34 genital disc precursor cells, while wild type embryos have only 22 at this stage.

(Chen et al., 2005)

Testes from males carrying temperature-sensitive dpp mutant alleles show displacement of the somatic hub and a reduction in the number of early germ cells. However, these effects are seen in both heterozygotes and homozygotes and at both permissive and restrictive temperatures, making it difficult to interpret their meaning.

(Schulz et al., 2004)

The hindgut is variable and severely deformed in mutant embryos, but hindgut boundary cell rows are still seen.

(Iwaki and Lengyel, 2002)

Clones in the adult abdomen that are triply mutant for Pka-C1^E95, wg^l-17 and dpp^unspecified have the same phenotype as single mutant Pka-C1^E95 clones.

(Struhl et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

dpp^unspecified is a non-enhancer of lethal | embryonic stage | maternal effect phenotype of Gug^unspecified

(Zhang et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

dpp^unspecified is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, nej^ΔBHQ.UAS

(Anderson et al., 2005)

Suppressor of

Statement

Reference

dpp^unspecified is a suppressor of amnioserosa phenotype of Med^c5

(Hudson et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

dpp^unspecified/dpp^unspecified Egfr^t1/Egfr^f11 double homozygotes show a simple additive phenotype.

(Diaz-Benjumea and Garcia-Bellido, 1990)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

dpp^KG08191

(Dworkin and Gibson, 2006)

Partially rescued by

dpp^unspecified is partially rescued by dpp^P23

(Gelbart, 1997.12.4)

dpp^unspecified is partially rescued by dpp^Sal20

(Gelbart, 1997.12.4)

dpp^unspecified is partially rescued by dpp^Sal20

(Newfeld et al., 1997)

dpp^unspecified is partially rescued by dpp^Sal20

(Padgett and Gelbart, 1995.3.25)

dpp^unspecified is partially rescued by dpp⁸³⁹¹

(Hoffmann and Goodman, 1987)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

dpp^-

(Umulis et al., 2006)

dpp^hin

(Srinivasan et al., 2002, Biehs et al., 1996)

dpp^unspecified

unspecified

(Struhl et al., 1997, Diaz-Benjumea and Garcia-Bellido, 1990)

Name Synonyms

Secondary FlyBase IDs

References (21)

Report Sections

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