FB2024_03 , released June 25, 2024
Allele: Dmel\vir5
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General Information
Symbol
Dmel\vir5
Species
D. melanogaster
Name
FlyBase ID
FBal0050753
Feature type
allele
Associated gene
Dmel\vir
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hilfiker et al., 1995)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Male homozygotes and male transheterozygotes with other EMS induced vir mutations die during larval or pupal stage, very few male escapers are present. Transheterozygotes with virts transform XX animals into intersexes at 29oC. Sxl+/Sxl+;vir5/virts and Sxlf1/Sxl+;vir5/vir+ are viable but doubly heterozygous Sxlf1/Sxl+;vir5/virts females are lethal. The presence of SxlM1, SxlM4 or SxlF1.hs failed to rescue female lethality in vir transheterozygotes.

      (Hilfiker et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      virunspecified/vir5 has lethal | female | larval stage phenotype, non-suppressible by SxlF1.hs

      (Hilfiker et al., 1995)

      virunspecified/vir5 has lethal | female | larval stage phenotype, non-suppressible by SxlM1

      (Hilfiker et al., 1995)

      virunspecified/vir5 has lethal | female | larval stage phenotype, non-suppressible by SxlM4

      (Hilfiker et al., 1995)

      vir5 has lethal | female | larval stage phenotype, non-suppressible by msl-1γ222

      (Hilfiker et al., 1995)

      vir5 has lethal | female | larval stage phenotype, non-suppressible by msl-2γ136

      (Hilfiker et al., 1995)

      vir5 has lethal | female | larval stage phenotype, non-suppressible by mle9

      (Hilfiker et al., 1995)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Female lethality cannot be rescued by msl-1γ222, msl-2γ136 or mle9 mutations. The presence of SxlM1, SxlM4 or SxlF1.hs failed to rescue female lethality in virtransheterozygotes.

      (Hilfiker et al., 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      vir5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)