FB2024_03 , released June 25, 2024
Allele: Dmel\psqF112
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General Information
Symbol
Dmel\psqF112
Species
D. melanogaster
Name
FlyBase ID
FBal0050311
Feature type
allele
Associated gene
Dmel\psq
Associated Insertion(s)
P{PZ}psqF112
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Weber et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{PZ}psqF112
Cytology
Description

P-element insertion 224bp downstream of exon 1B.

(Weber et al., 1995)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos derived from psqfs1/psqF112 mutant females display terminal defects.

      (Grillo et al., 2011)

      Semilethal when heterozygous with Df(2R)17 or Df(2R)27. Viable over Df(2R)12 causing female sterility and maternal phenotypes. Escapers display a variety of adult phenotypes. Eyes display an irregular ommatidial array and photoreceptor cells 3 and 4 are often missing. Wings are shorter with thicker veins and notching along the margin. Legs are distorted. Macrochaetae on the dorsal head and thorax are kinked, branched or missing. Females exhibit rudimentary ovaries.

      (Weber et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      psq[+]/psqF112 is an enhancer of visible | dominant phenotype of Pc4

      (Huang et al., 2002)
      Suppressor of
      Statement
      Reference

      psq[+]/psqF112 is a suppressor of visible | adult stage phenotype of Marcal1UAS.cBa, Scer\GAL4Tub.PU

      (Morimoto et al., 2016)

      psq[+]/psqF112 is a suppressor of visible | adult stage phenotype of Hsap\SMARCAL1UAS.cBa, Scer\GAL4Bx-MS1096

      (Morimoto et al., 2016)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      psq[+]/psqF112 is an enhancer of leg phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psqF112 is an enhancer of sex comb | ectopic phenotype of Pc4

      (Huang et al., 2002)
      Suppressor of
      Statement
      Reference

      psq[+]/psqF112 is a suppressor of wing vein | adult stage phenotype of Marcal1UAS.cBa, Scer\GAL4Tub.PU

      (Morimoto et al., 2016)

      psq[+]/psqF112 is a suppressor of wing vein | adult stage phenotype of Hsap\SMARCAL1UAS.cBa, Scer\GAL4Bx-MS1096

      (Morimoto et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The formation of ectopic wing veins observed in adult flies expressing Marcal1Scer\UAS.cBa under the control of Scer\GAL4tub.PU is ameliorated by combination with a single copy of psqF112.

      (Morimoto et al., 2016)

      The ectopic sex comb phenotype seen on the second and third legs of Pc4/+ males is dominantly enhanced by psqF112.

      (Huang et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference

      The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1Scer\UAS.cBa under the control of Scer\GAL4Bx-MS1096 is ameliorated by combination with a single copy of psqF112.

      (Morimoto et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise P-element excision reverts the mutant phenotype.

      (Weber et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      F112
      (Huang et al., 2002)
      psqF112
      (Grillo et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)