Clonal analysis reveals that spen is required for eye development. Homozygous ommatidia lack either R7 or one of more other photoreceptors. Embryos derived from homozygous germline clones show no indication of absent or abnormal tor pathway signalling.
Dominantly enhances the rough eye phenotype of phl::tor12D.sev. Modifies the eye phenotype of phl12. Enhances phl12 phenotype resulting in synthetic lethality.
Alleles of spen exhibit complex complementation relationships. spen14O1 and spen16H1 partially complement, as do spen14O1 and spen16T1. spen16H1 completely fails to complement spen16T1.