FB2024_03 , released June 25, 2024
Allele: Dmel\wHSBJ
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General Information
Symbol
Dmel\wHSBJ
Species
D. melanogaster
Name
heat shock of Brad Jones
FlyBase ID
FBal0046756
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{HSBJCaSpeR}
P{HSBJα}
P{HSBJβ}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Zhang and Odenwald, 1995)
Progenitor genotype
w+mC
(Zhang and Odenwald, 1995)
Carried in construct
P{HSBJCaSpeR}
P{HSBJα}
P{HSBJβ}
Cytology
Description

Construct: Hsp70 promoter sequences of vector "pHSBJ" drive the expression of w+mC.

(Zhang and Odenwald, 1995)
Allele components
Component
Use(s)
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Transformant heat shocked males exhibit homosexual courtship behaviour.

      (Zhang and Odenwald, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      wHSBJ is a suppressor of abnormal eye color phenotype of g50e

      (Lloyd et al., 2002)

      wHSBJ is a suppressor of abnormal eye color phenotype of g53d

      (Lloyd et al., 2002)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      wHSBJ is a suppressor of pigment cell phenotype of g50e

      (Lloyd et al., 2002)

      wHSBJ is a suppressor of pigment cell phenotype of g53d

      (Lloyd et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of the wHSBJ transgene increases the amount of red pigment in both male and female w+, g50e flies. Additionally, this transgene is able to increase the amount of red pigment in the eyes of g53d flies.

      (Lloyd et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      wHSBJ rescues w1118

      (Lee et al., 2008)
      Partially rescues

      wHSBJ partially rescues w1

      (Lloyd et al., 2002)
      Comments

      One copy of wHSBJ restores courtship disinhibition after repeated ethanol exposure (observed as intermale courtship) in w1118 males.

      (Lee et al., 2008)

      One copy of the wHSBJ transgene can restore the amount of pigment from <1% to 33% in female flies and 96% in male flies with a w1 homozygous genotype.

      (Lloyd et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      hs-mw+
      (Lee et al., 2008)
      wHSBJ
      Name Synonyms
      heat shock of Brad Jones
      (Zhang and Odenwald, 1995)
      Secondary FlyBase IDs
        References (3)