FlyBase Allele Report: Dmel\asp[DD3]

General Information

Symbol

Dmel\asp^DD3

Species

D. melanogaster

Name

FlyBase ID

FBal0045364

Feature type

allele

Associated gene

Dmel\asp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(White-Cooper, 1996.4.29, White-Cooper et al., 1996)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile (with Df(3R)Hd^γ1)

(White-Cooper et al., 1996)

lethal

(White-Cooper et al., 1996)

lethal | maternal effect | recessive

(Inoue and Glover, 1998)

male sterile

(White-Cooper et al., 1996)

viable (with Df(3R)Hd^γ1)

(White-Cooper et al., 1996)

visible | recessive

(Inoue and Glover, 1998)

Phenotype Manifest In

embryonic/larval brain

(White-Cooper et al., 1996)

eye

(White-Cooper et al., 1996)

macrochaeta

(White-Cooper et al., 1996)

Detailed Description

Statement

Reference

Transheterozygotes are female sterile and semi-lethal, exhibit rough eyes and bristle defects, brain defects and meiosis is mostly normal (motile sperm) with some nondisjunction. Homozygous lethality occurs during larval and pupal stages. Heterozygotes with Df(3R)Hd^γ1 are viable but female sterile.

(White-Cooper et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

asp^DD3 has eye phenotype, enhanceable by rl¹

(Inoue and Glover, 1998)

asp^DD3 has wing phenotype, enhanceable by rl¹

(Inoue and Glover, 1998)

Suppressed by

Statement

Reference

asp^DD3 has eye phenotype, suppressible by rl^Su14

(Inoue and Glover, 1998)

asp^DD3 has wing phenotype, suppressible by rl^Su14

(Inoue and Glover, 1998)

asp^DD3 has eye phenotype, suppressible by Dsor1^Su1

(Inoue and Glover, 1998)

asp^DD3 has wing phenotype, suppressible by Dsor1^Su1

(Inoue and Glover, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

rl¹ recessively enhances the eye and wing defects associated with the asp¹/asp^DD3 mutant. rl^Su14 and Dsor1^Su1 dominantly suppress the morphological defects and sterility of asp¹/asp^DD3 mutants. Survival of embryos from asp¹/asp^DD3 females is increased in double mutants with Dsor1^Su1, fewer have no nuclei.

(Inoue and Glover, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Phenotype assayed in trans with a multiple mutant chromosome carrying mutations of polo, mgr, asp, stg and gnu.

(White-Cooper et al., 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

asp^DD3

asp^dd3

(Schnorrer et al., 2002, Inoue and Glover, 1998, White-Cooper et al., 1996)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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