FB2024_03 , released June 25, 2024
Allele: Dmel\Doa04743
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General Information
Symbol
Dmel\Doa04743
Species
D. melanogaster
Name
FlyBase ID
FBal0042514
Feature type
allele
Associated gene
Dmel\Doa
Associated Insertion(s)
P{PZ}Doa04743
Carried in Construct
Also Known As
l(3)04743
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Doa04743
Cytology
Description

The P{PZ} element is inserted 655 nucleotides 5' to the first non-coding exon of the 105kDa Doa coding transcript and 2191 nucleotides 5' to its initiating AUG.

(Kpebe and Rabinow, 2008)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In Doa7/Doa04743 mutants where the Doa7 allele is from the mother only males are observed. These have extremely rough eyes, ectopic wing veins, missing head, scutellar and thoracic bristles. When the Doa04743 allele comes from the mother there are no survivors.

      In DoaDem/Doa04743 mutants where the DoaDem allele is from the mother only rare pupae eclose and weak adults die quickly.The flies exhibit rough eyes, missing bristles and an incomplete L5 wing vein. When the Doa04743 allele comes from the mother there are no survivors.

      (Kpebe and Rabinow, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Doa01705b

      (BDGP Project Members, 1994-1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      A. Spradling.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Doa04743
      l(3)04743
      (Spradling et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)