FB2024_03 , released June 25, 2024
Allele: Ecol\lacZsvp-3
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General Information
Symbol
Ecol\lacZsvp-3
Species
E. coli
Name
FlyBase ID
FBal0041983
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{HZ}svp3
Carried in Construct
Also Known As
svp-lacZ, H162, seven up-lacZ, Seven-up-lacZ
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Strutt et al., 1997, Younossi-Hartenstein et al., 1997, Skeath et al., 1995, Chu-LaGraff and Doe, 1993, Doe, 1992, Mlodzik et al., 1990)
Progenitor genotype
Associated Insertion(s)
P{HZ}svp3
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{HZ}
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      No Assay Recorded
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      neuroblast NB3-2
      (Chu-LaGraff and Doe, 1993)
      neuroblast NB7-2
      (Chu-LaGraff and Doe, 1993)
      embryonic stage 9 -- 11
      neuroblast NB3-2
      (Doe, 1992)
      neuroblast NB7-2
      (Doe, 1992)
      neuroblast NB5-3
      (Doe, 1992)
      embryonic stage 10 -- 11
      neuroblast NB3-5
      (Doe, 1992)
      neuroblast NB5-6
      (Doe, 1992)
      embryonic stage 11
      neuroblast NB2-3

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB1-1
      (Doe, 1992)
      neuroblast NB3-3

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB5-4

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB4-4

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB6-4

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB4-2

      Comment: late stage 11

      (Doe, 1992)
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      neuroblast | restricted
      (Mlodzik et al., 1990)
      ventral neurectoderm
      (Chu-LaGraff and Doe, 1993)
      neuroblast NB5-3
      (Chu-LaGraff and Doe, 1993)
      embryonic stage 8 -- 11
      neuroblast NB5-2
      (Doe, 1992)
      embryonic stage 9 -- 11
      neuroblast NB7-1
      (Doe, 1992)
      neuroblast NB2-5
      (Doe, 1992)
      procephalic neuroblast | subset
      (Urbach and Technau, 2003, Urbach et al., 2003)
      deutocerebral neuroblast | subset
      (Urbach and Technau, 2003, Hartenstein et al., 1994)
      neuroblast NB7-4
      (Doe, 1992)
      tritocerebral neuroblast | subset
      (Urbach and Technau, 2003, Hartenstein et al., 1994)
      protocerebral neuroblast | subset
      (Urbach and Technau, 2003, Hartenstein et al., 1994)
      embryonic stage 10 -- 11
      neuroblast NB6-2
      (Doe, 1992)
      neuroblast NB4-1
      (Doe, 1992)
      embryonic stage 11
      neuroblast NB5-1

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB2-4

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB4-3

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB3-4

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB5-5

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB3-1

      Comment: late stage 11

      (Doe, 1992)
      neuroblast NB7-3

      Comment: late stage 11

      (Doe, 1992)
      embryonic stage 12 -- 16
      embryonic dorsal vessel | restricted
      (Ryan et al., 2007)
      embryonic stage 13 -- 16
      larval B-subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      larval A-subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      lateral ventral subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      medial dorsal subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      dorsal lateral subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      ventral lateral subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      medial ventral subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      medial lateral subperineurial glial cell
      (Beckervordersandforth et al., 2008)
      dorsal channel glial cell
      (Beckervordersandforth et al., 2008)
      ventral channel glial cell
      (Beckervordersandforth et al., 2008)
      CNS surface glial cell
      (Beckervordersandforth et al., 2008)
      larval channel glial cell
      (Beckervordersandforth et al., 2008)
      embryonic/larval neuron
      (Beckervordersandforth et al., 2008)
      lateral intersegmental nerve root glial cell
      (Beckervordersandforth et al., 2008)
      embryonic stage 13 -- 17
      embryonic peripheral glial cell 2
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 3
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 4
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 6
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 7
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 8
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 10
      (von Hilchen et al., 2008)
      third instar larval stage
      photoreceptor cell R4 | presumptive
      (Mlodzik et al., 1990)
      photoreceptor cell R6 | presumptive
      (Mlodzik et al., 1990)
      photoreceptor cell R3 | presumptive
      (Mlodzik et al., 1990)
      photoreceptor cell R1 | presumptive
      (Mlodzik et al., 1990)
      eye disc posterior to the morphogenetic furrow
      (Mlodzik et al., 1990)
      embryonic ostial cardioblast
      (Molina and Cripps, 2001)
      Additional Information
      Statement
      Reference

      Seven bilateral pairs of EcollacZsvp-3-positive cells are visible in the embryonic dorsal vessel.

      (Ryan et al., 2007)

      Expression of a svp-lacZ reporter occurs in an increasing number of procephalic neuroblasts through stages 9-11. At the end of neuroblast development in late stage 11 svp reporter expression is detected in 39 neuroblasts per hemisphere.

      (Urbach et al., 2003)

      Reporter expression is observed in two pairs of cardial cells per segment. These correspond to the locations of the ostia.

      (Molina and Cripps, 2001)

      Expression in procephalic neuroblasts stage 9-11: tritocerebrum - d6, d8, v2; deuterocerebrum - d1, d3, d6-8, d13, v2-8; protocerebrum - ad1, ad7, ad8, ad15, cd2, cd4, cd6, cd8, cd9, cd18, cd21, cv3, cv6, cv7, cv9, pd3, pd9, pd15, pd16, pd18, pd20, pv2

      (Hartenstein et al., 1994)

      EcollacZsvp-3 expression was usedas a cell marker for intermediate column neuroblasts 3-2, 5-3, and 7-2,but not 4-2 or 6-2. In wg mutant embryos, expression is seen inneuroblast 4-2 in addition to 3-2, 5-3, and 7-2. 6-2 never forms.

      (Chu-LaGraff and Doe, 1993)

      Enhancer trap expression is observed in a specified subset of neuroblasts in embryonic stages 8-11. (see also FBrf 51362)

      (Doe, 1992)

      This EcollacZ enhancer trap drivesexpression in photoreceptor cell precursors R1, R3, R4 and R6.

      (Mlodzik et al., 1990)
       
      Marker for
      Dd1 neuroblast
      (Urbach and Technau, 2003)
      Dd13 neuroblast
      (Urbach and Technau, 2003)
      Dd3 neuroblast
      (Urbach and Technau, 2003)
      Dd6 neuroblast
      (Urbach and Technau, 2003)
      Dd7 neuroblast
      (Urbach and Technau, 2003)
      Dd8 neuroblast
      (Urbach and Technau, 2003)
      Dv2 neuroblast
      (Urbach and Technau, 2003)
      Dv3 neuroblast
      (Urbach and Technau, 2003)
      Dv4 neuroblast
      (Urbach and Technau, 2003)
      Dv5 neuroblast
      (Urbach and Technau, 2003)
      Dv6 neuroblast
      (Urbach and Technau, 2003)
      Dv7 neuroblast
      (Urbach and Technau, 2003)
      Dv8 neuroblast
      (Urbach and Technau, 2003)
      Pad1 neuroblast
      (Urbach and Technau, 2003)
      Pad15 neuroblast
      (Urbach and Technau, 2003)
      Pad7 neuroblast
      (Urbach and Technau, 2003)
      Pad8 neuroblast
      (Urbach and Technau, 2003)
      Pcd18 neuroblast
      (Urbach and Technau, 2003)
      Pcd2 neuroblast
      (Urbach and Technau, 2003)
      Pcd21 neuroblast
      (Urbach and Technau, 2003)
      Pcd4 neuroblast
      (Urbach and Technau, 2003)
      Pcd6 neuroblast
      (Urbach and Technau, 2003)
      Pcd8 neuroblast
      (Urbach and Technau, 2003)
      Pcd9 neuroblast
      (Urbach and Technau, 2003)
      Pcv1 neuroblast
      (Urbach and Technau, 2003)
      Pcv3 neuroblast
      (Urbach and Technau, 2003)
      Pcv6 neuroblast
      (Urbach and Technau, 2003)
      Pcv7 neuroblast
      (Urbach and Technau, 2003)
      Pcv9 neuroblast
      (Urbach and Technau, 2003)
      Ppd15 neuroblast
      (Urbach and Technau, 2003)
      Ppd16 neuroblast
      (Urbach and Technau, 2003)
      Ppd18 neuroblast
      (Urbach and Technau, 2003)
      Ppd20 neuroblast
      (Urbach and Technau, 2003)
      Ppd3 neuroblast
      (Urbach and Technau, 2003)
      Ppd9 neuroblast
      (Urbach and Technau, 2003)
      Td6 neuroblast
      (Urbach and Technau, 2003)
      Td8 neuroblast
      (Urbach and Technau, 2003)
      Tv1 neuroblast
      (Urbach and Technau, 2003)
      cardioblast
      (Albrecht et al., 2006)
      embryonic peripheral glial cell 10
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 2
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 3
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 4
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 6
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 7
      (von Hilchen et al., 2008)
      embryonic peripheral glial cell 8
      (von Hilchen et al., 2008)
      Reflects expression of
      svp
      (Beckervordersandforth et al., 2008, Urbach and Technau, 2003, Urbach et al., 2003, Molina and Cripps, 2001, Hartenstein et al., 1994, Doe, 1992, Mlodzik et al., 1990)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Ecol\lacZsvp-3
      H162
      (Zhang and Lu, 2000, Chu et al., 1998, Younossi-Hartenstein et al., 1997, Hartenstein et al., 1994)
      lacZsvp-3
      lacZsvp-H162
      svp-lacZ
      (Skeath, 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (44)