FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term neuroblast NB2-3 ID (Ontology) FBbt:00001421 (Fly Anatomy)
Definition Neuroblast that delaminates at S5 and only produces a primary lineage in thoracic segments (Schmid et al., 1999; Birkholz et al., 2013; Urbach et al., 2016). In abdominal hemisegments only a single large neuroblast is observed at embryonic stage 17, which either does not divide or all progeny die (Schmid et al., 1999). In the embryo, it generates three cells thought to be latent leg motorneurons and 2-4 small interneurons (Schmid et al., 1999). In the larva, this neuroblast resumes proliferation in all thoracic segments and generates postembryonic lineage 15 (Lacin and Truman, 2016).[ FlyBase:FBrf0055900 FlyBase:FBrf0084809 FlyBase:FBrf0112030 FlyBase:FBrf0221210 FlyBase:FBrf0228122 FlyBase:FBrf0231327 FlyBase:FBrf0232096 ]
Also Known As "lineage 15 neuroblast" ; "neuroblast 15"
Comment Originally referred to as NB1-2 by Doe (1992), this was renamed to NB2-3 by Broadus et al. (1995) to keep the names of row 2 neuroblasts consistent with their position in Schistocerca. Birkholz et al. (2015) suggest that NB2-3 does not generate a postembryonic lineage and NB3-2 generates postembryonic lineage 15, but Lacin and Truman (2016) provide lineage tracing and marker data showing that NB2-3 generates lineage 15.
Links to Extrernal Ontologies
VFB:FBbt_00001421
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       1
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
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Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 neuroblast NB2-3 (all annotations which use CV term, excluding "NOT" statements)       2      2      5      4      3
Spanning Tree (Parents/Children)
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central nervous system
 |__segmentally-repeated neuroblast__
neuroblast                           |
 |__stage 5 neuroblast_______________|
 |__segmentally-repeated neuroblast__|
                                     neuroblast NB2-3  16 rec.
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Is a stage 5 neuroblast
segmentally-repeated neuroblast
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VFB:FBbt_00001421