FB2024_03 , released June 25, 2024
Allele: Dmel\per+t8.0
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General Information
Symbol
Dmel\per+t8.0
Species
D. melanogaster
Name
FlyBase ID
FBal0039742
Feature type
allele
Associated gene
Dmel\per
Associated Insertion(s)
Carried in Construct
P{per8.0(PA)}
P{per8.0}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cooper et al., 1994, Liu et al., 1991, Zerr et al., 1990, Zehring et al., 1984)
Progenitor genotype
per+t14.6
(Zehring et al., 1984)
Carried in construct
P{per8.0(PA)}
P{per8.0}
Cytology
Description

8.0kb per DNA, 5' end begins within the first intron so contains all coding regions and 3' flanking sequence.

(Cooper et al., 1994)

8.0kb genomic fragment containing the entire per coding region, but lacking all 5' sequences, the first exon and approximately 1kb of the 2.3kb first intron.

(Liu et al., 1991)

Included within 8.0kb genomic fragment derived by deletion of 6.6kb of per+t14.6 from the end closest to the 3' end of the per transcription unit.

(Zehring et al., 1984)
Allele components
Component
Use(s)
Regulatory region(s)
per
Encoded product / tool
per
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      per01 per+t8.0 flies have an average period somewhat longer than per01 per+t13.2 flies.

      (Liu et al., 1991)

      per01 flies transformed with this allele are frequently rhythmic, though circadian periods are slightly longer than the normal range.

      (Yu et al., 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      per+t8.0 rescues per01

      (Cooper et al., 1994)

      per+t8.0 rescues per01

      (Zehring et al., 1984)
      Comments

      Rescues the arrhythmicity of per01 flies.

      (Cooper et al., 1994)

      Rescues the arhythmicity of locomotor behavior and courtship song of per01 flies.

      (Zehring et al., 1984)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      per expression, with respect to behavioural circadian rhythms, is dosage compensated.

      (Cooper et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      per+t8.0
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0035358
      References (6)