FB2024_03 , released June 25, 2024
Allele: Dmel\per+t14.6
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General Information
Symbol
Dmel\per+t14.6
Species
D. melanogaster
Name
FlyBase ID
FBal0039740
Feature type
allele
Associated gene
Dmel\per
Associated Insertion(s)
Carried in Construct
P{per14.6}
Key Links
Transgenic product class
genomic_DNA
(Zehring et al., 1984)
wild_type
(Zehring et al., 1984)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Zehring et al., 1984)
wild_type
(Zehring et al., 1984)
Mutagen
in vitro construct
(Cooper et al., 1994, Dushay et al., 1990, Hardin et al., 1990, Zerr et al., 1990, Citri et al., 1987, Zehring et al., 1984)
Progenitor genotype
Carried in construct
P{per14.6}
Cytology
Description

14.6kb per DNA, 5' end begins within the first intron so contains all coding regions and 3' flanking sequence.

(Cooper et al., 1994)

Included within 14.6kb genomic fragment.

(Zehring et al., 1984)
Allele components
Component
Use(s)
Regulatory region(s)
per
Encoded product / tool
per
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Long cycle duration, the evening peak of activity is shifted to a later time than wild type.

      (Hamblen-Coyle et al., 1992)

      Males have slower clocks than the normal 24 hour.

      (Gailey et al., 1991)

      Restores circadian phenotype to mutant per flies.

      (Citri et al., 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      per+t14.6 rescues per01

      (Cooper et al., 1994)

      per+t14.6 rescues per01

      (Zehring et al., 1984)
      Partially rescues

      per+t14.6 partially rescues per01

      (Gailey et al., 1991)
      Comments

      Rescues the arrhythmicity of per01 flies.

      (Cooper et al., 1994)

      Transgenic per01 flies are almost always rhythmic but the resulting circadian periodicity is longer than in normal flies.

      (Gailey et al., 1991)

      Rescues the arhythmicity of locomotor behavior and courtship song of per01 flies.

      (Zehring et al., 1984)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      per expression, with respect to behavioural circadian rhythms, is dosage compensated.

      (Cooper et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      per+t14.6
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0035358
      References (9)