FB2024_03 , released June 25, 2024
Allele: Dmel\klarmarb-BX12
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General Information
Symbol
Dmel\klarmarb-BX12
Species
D. melanogaster
Name
FlyBase ID
FBal0039627
Feature type
allele
Associated gene
Dmel\klar
Associated Insertion(s)
Carried in Construct
Also Known As
klarmBX12
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Fischer-Vize and Mosley, 1994)
Mutagen
X ray
(Fischer-Vize and Mosley, 1994)
Progenitor genotype
Cytology
Description

Contains a deletion between amino acid residue 2212 and residue 2226.

(Guo et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      klarmarb-BX12 embryos show normal lipid droplet transport.

      (Guo et al., 2005)

      Rough eye phenotype.

      (Fischer-Vize and Mosley, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      klarmarb-BX12 has eye phenotype, non-enhanceable by Msp300compl

      (Technau and Roth, 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Female Msp-300compl;klarmarb-BX12 double mutants lay normal eggs and exhibit wild-type egg chambers. In addition, no defects are found in Msp-300compl mutant follicle cell clones generated in klarmarb-BX12 homozygous mutant females.

      Induction of Msp-300compl mutant cell clones in a klarmarb-BX12 homozygous mutant background in the wing imaginal discs does not affect nuclear positioning.

      Msp-300compl mutant cell clones do not enhance the klarmarb-BX12 mutant rough eye phenotype.

      Msp-300compl;klarmarb-BX12 double mutants do not exhibit any difference in nuclear morphology (or localisation) at any time point during early embryogenesis.

      Female Msp-3005prime;klarmarb-BX12 double mutants lay normal eggs and exhibit wild-type egg chambers.

      Female Msp-3003prime;klarmarb-BX12 double mutants lay normal eggs and exhibit wild-type egg chambers.

      The rough eye phenotype of Df(2R)CG3287-koi mutant is not enhanced in Df(2R)CG3287-koi; klarmarb-BX12 double mutants.

      (Technau and Roth, 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      klarmBX12
      (Technau and Roth, 2008, Guo et al., 2005)
      klarmarb-BX12
      klsmarb-BX12
      marbBX12
      Name Synonyms
      Secondary FlyBase IDs
        References (3)