FlyBase Allele Report: Dmel\por[PB16]

General Information

Symbol

Dmel\por^PB16

Species

D. melanogaster

Name

FlyBase ID

FBal0032474

Feature type

allele

Associated gene

Dmel\por

Associated Insertion(s)

Carried in Construct

Also Known As

porc^PB16

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Kadowaki et al., 1996, Eberl et al., 1992)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | embryonic stage | rescuable maternal effect

(Kadowaki et al., 1996)

lethal | pupal stage | recessive

(Eberl et al., 1992)

lethal | recessive

(Kadowaki et al., 1996)

lethal | rescuable maternal effect

(Eberl et al., 1992)

segment polarity phenotype

(Kadowaki et al., 1996)

Phenotype Manifest In

abdominal 1 ventral denticle belt

(Noordermeer et al., 1994)

abdominal 2 ventral denticle belt

(Noordermeer et al., 1994)

abdominal 3 ventral denticle belt

(Noordermeer et al., 1994)

abdominal 4 ventral denticle belt

(Noordermeer et al., 1994)

abdominal 5 ventral denticle belt

(Noordermeer et al., 1994)

abdominal 6 ventral denticle belt

(Noordermeer et al., 1994)

abdominal 7 ventral denticle belt

(Noordermeer et al., 1994)

antenna

(Kadowaki et al., 1996)

embryo

(Kadowaki et al., 1996)

embryonic/first instar larval cuticle | germline clone

(Tanaka et al., 2000)

embryonic/larval tracheal dorsal trunk | germline clone

(Llimargas, 2000)

embryonic/larval tracheal system | germline clone

(Llimargas, 2000)

embryonic head | germline clone

(Tanaka et al., 2000)

leg

(Kadowaki et al., 1996)

leg | distal

(Kadowaki et al., 1996)

presumptive embryonic/larval central nervous system

(Tanaka et al., 2002)

sex comb

(Kadowaki et al., 1996)

tergite

(Kadowaki et al., 1996)

unguis | increased number

(Kadowaki et al., 1996)

ventral denticle belt

(Kadowaki et al., 1996, Manoukian et al., 1995)

ventral denticle belt | germline clone

(Tanaka et al., 2000)

wing

(Kadowaki et al., 1996)

wing & macrochaeta

(Kadowaki et al., 1996)

Detailed Description

Statement

Reference

The shape and number of axon tracts is somewhat disorganised in mutant embryos.

(Tanaka et al., 2002)

Embryos derived from homozygous female germline clones show defects in tracheal invagination, branch fusion and dorsal trunk formation.

(Llimargas, 2000)

Homozygous embryos derived from homozygous female germline clones lack the naked posterior half of each segment and lack denticle diversity, segmental furrows and terminal structures.

(Tanaka et al., 2000)

Lethality occurs at the larval or pupal stages. A few survive through metamorphosis before dying. These adults display nicked wings and lack marginal bristles, they lack antennal structures and tergites are incomplete. Legs are bulbous and truncated, the claw is duplicated and the number of sex combs is reduced to 1-3. Mosaic clones on the dorsal or ventral prothoracic leg surface cause no mutant phenotype. Homozygous embryos exhibit a wg-like segment polarity phenotype. Gynandromorphs exhibit a wild-type pattern of denticle belts.

(Kadowaki et al., 1996)

Embryos exhibit a lawn of denticle belts.

(Manoukian et al., 1995)

Double mutants of wg^hs.PN and arm^25B show some restoration of the segmental denticle phenotype.

(Noordermeer et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

por^PB16 is an enhancer of visible phenotype of Nsf2^EQ.UAS, Scer\GAL4^bbg-C96

(Stewart et al., 2001)

Phenotype Manifest In

Enhancer of

Statement

Reference

por^PB16 is an enhancer of wing margin phenotype of Nsf2^EQ.UAS, Scer\GAL4^bbg-C96

(Stewart et al., 2001)

Suppressor of

Statement

Reference

por^PB16 is a suppressor of larval anterior commissure phenotype of Scer\GAL4^sim.PS, Wnt5^UAS.cFa

(Fradkin et al., 2004)

NOT Suppressor of

Statement

Reference

por^PB16 is a non-suppressor of abdominal 1 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

por^PB16 is a non-suppressor of abdominal 2 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

por^PB16 is a non-suppressor of abdominal 3 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

por^PB16 is a non-suppressor of abdominal 4 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

por^PB16 is a non-suppressor of abdominal 5 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

por^PB16 is a non-suppressor of abdominal 6 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

por^PB16 is a non-suppressor of abdominal 7 ventral denticle belt phenotype of sgg^M11

(Siegfried et al., 1994)

Additional Comments

Genetic Interactions

Statement

Reference

Embryos derived from homozygous doubly mutant germ lines, receiving neither maternal or zygotic wild type product, for sgg^M11 and por^PB16 lack denticles on the ventral cuticle.

(Siegfried et al., 1994)

Xenogenetic Interactions

Statement

Reference

Injection of Mmus\porc^A.cTa, Mmus\porc^B.cTa, Mmus\porc^C.cTa or Mmus\porc^D.cTa RNA into por^PB16 embryos derived from por^PB16 female germline clones partially rescues the por mutant phenotype.

(Tanaka et al., 2000)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

4768

w¹ ovo^svb-* por^PB16 P{FRT(w^hs)}9-2/FM7a

Notes on Origin

Discoverer

Ferrus.

(Eberl et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

por^PB16

porc^PB16

(Fradkin et al., 2004, Zhai et al., 2004, Tanaka et al., 2002, Strigini and Cohen, 2000, Tanaka et al., 2000, Kadowaki et al., 1996, Manoukian et al., 1995, Hooper, 1994, Siegfried et al., 1994)

porc^pb18

(Stewart et al., 2001)

Name Synonyms

Secondary FlyBase IDs

References (16)

Report Sections

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