FB2024_03 , released June 25, 2024
Allele: Dmel\Mi-21
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General Information
Symbol
Dmel\Mi-21
Species
D. melanogaster
Name
FlyBase ID
FBal0031976
Feature type
allele
Associated gene
Dmel\Mi-2
Associated Insertion(s)
P{lArB}Mi-21
Carried in Construct
Also Known As
l(3)A154.3M3
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kim et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{lArB}Mi-21
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lArB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous female germline clones do not produce any eggs.

      (Kehle et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Mi-21 is an enhancer of visible | dominant phenotype of KrIf-1

      (Abrell et al., 2000)

      Mi-21/Mi-2[+] is an enhancer of visible | dominant phenotype of KrIf-1

      (Carrera et al., 1998)

      Mi-21/Mi-2[+] is an enhancer of visible | dominant | homeotic phenotype of Pc4

      (Kehle et al., 1998)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Mi-21 is an enhancer of eye phenotype of KrIf-1

      (Abrell et al., 2000)

      Mi-21 is an enhancer of ommatidium phenotype of KrIf-1

      (Abrell et al., 2000)

      Mi-21/Mi-2[+] is an enhancer of eye phenotype of KrIf-1

      (Carrera et al., 1998)

      Mi-21/Mi-2[+] is an enhancer of mesothoracic leg phenotype of Pc4

      (Kehle et al., 1998)

      Mi-21/Mi-2[+] is an enhancer of metathoracic leg phenotype of Pc4

      (Kehle et al., 1998)

      Mi-21/Mi-2[+] is an enhancer of sex comb | ectopic phenotype of Pc4

      (Kehle et al., 1998)
      Suppressor of
      Statement
      Reference

      Mi-21/Mi-2[+] is a suppressor of adult abdominal segment 4 | ectopic phenotype of E(z)Trm

      (Bajusz et al., 2001)

      Mi-21/Mi-2[+] is a suppressor of adult abdominal segment 5 phenotype of E(z)Trm

      (Bajusz et al., 2001)

      Mi-21/Mi-2[+] is a suppressor of adult mesothoracic segment | ectopic phenotype of E(z)Trm

      (Bajusz et al., 2001)

      Mi-21/Mi-2[+] is a suppressor of adult metathoracic segment phenotype of E(z)Trm

      (Bajusz et al., 2001)

      Mi-21/Mi-2[+] is a suppressor of adult prothoracic segment phenotype of E(z)Trm

      (Bajusz et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The formation of extra sex combs on the second and third legs in Pc4/+ flies is dominantly enhanced by Mi-2K1.

      (Kehle et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      Mi-21 is partially rescued by Mi-2arm.PK

      (Kehle et al., 1998)
      Comments

      The egg laying phenotype is rescued by Mi-2arm.PK; normally shaped eggs are produced, but no embryos are obtained.

      (Kehle et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      W. Gehring.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      Reported As
      Symbol Synonym
      Mi-21
      Pha1
      (Bellen et al., 1989)
      dMi-21
      (Read et al., 2005)
      dMi-22
      (Kehle et al., 1998)
      dMi1
      (Bajusz et al., 2001)
      l(3)A154.3M3
      (Abrell et al., 2000, Carrera et al., 1998, Kehle et al., 1998)
      l(3)A154.3M31
      pha1
      (Kim et al., 1997)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)