FB2024_03 , released June 25, 2024
Allele: Dmel\Asx9
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General Information
Symbol
Dmel\Asx9
Species
D. melanogaster
Name
FlyBase ID
FBal0029009
Feature type
allele
Associated gene
Dmel\Asx
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Sinclair et al., 1992)
Mutagen
gamma ray
(Sinclair et al., 1992)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      More severe Asx phenotype than Asx- deletion and also a more severe transformation of thoracic segments towards abdominal segments. Segmentation defects are also present: missing segments, midline denticles and hemisegments. Heterozygous adults have a mild transformation of A4 to A5 in males.

      (Sinclair et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Asx[+]/Asx9 is a suppressor of visible phenotype of tant2

      (Dietrich et al., 2001)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Asx9 is an enhancer of sex comb phenotype of Pc4

      (Milne et al., 1999)
      Suppressor of
      Statement
      Reference

      Asx[+]/Asx9 is a suppressor of interocellar bristle phenotype of tant2

      (Dietrich et al., 2001)
      Other
      Statement
      Reference

      Asx9, sxc3 has haltere phenotype

      (Milne et al., 1999)

      Asx9, sxc3 has abdominal segment 4 phenotype

      (Milne et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhances the trx-G homeotic transformations of Df(3R)red1. Strongly enhances the extra sex comb phenotype of Pc4. Double heterozygotes with sxc3 show reduced viability and survivors show transformations typical of Pc-G mutants including transformation of A4 to A5. Most also show haltere to wing transformations typical of trx-G mutants.

      (Milne et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Asx9
      Name Synonyms
      Secondary FlyBase IDs
        References (3)