FB2024_03 , released June 25, 2024
Allele: Dmel\Hsp83j5C2
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General Information
Symbol
Dmel\Hsp83j5C2
Species
D. melanogaster
Name
FlyBase ID
FBal0028382
Feature type
allele
Associated gene
Dmel\Hsp83
Associated Insertion(s)
P{lacW}Hsp83j5C2
Carried in Construct
Also Known As
l(3)j5C2, j5C2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{lacW}Hsp83j5C2
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      76% of Hsp8308445/Hsp83j5C2 flies show a loss of locomotor behavioral rhythms under free-running conditions (after entrainment in light-dark cycles).

      Hsp8308445/Hsp83j5C2 flies show a reduced fraction of flies with rhythmic locomotor activity in light-dark cycles (47% rhythmic) compared to control flies (88%-95% rhythmic).

      Hsp8308445/Hsp83j5C2 mutants show highly variable locomotor activity patterns, including fully rhythmic, arrhythmic, and complex behavioral profiles, in contrast to wild-type flies, which show little variation among individuals.

      (Hung et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      Hsp83j5C2/Hsp83[+] is a non-enhancer of embryonic abdominal segment | maternal effect phenotype of nanosΔBX, nanosBN

      (Song et al., 2007)
      Suppressor of
      Statement
      Reference

      Hsp83j5C2/Hsp83[+] is a suppressor of arista | increased number phenotype of obk1

      (Atallah et al., 2004)
      NOT Suppressor of
      Statement
      Reference

      Hsp83j5C2/Hsp83[+] is a non-suppressor of embryonic abdominal segment | maternal effect phenotype of nanosΔBX, nanosBN

      (Song et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The mutant abdominal segmentation phenotype seen in females carrying nosΔBX in a nosBN/nosBN background is not affected if the females also carry one copy of Hsp83j5C2.

      (Song et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      L. and Y. Jan.

      Comments
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      References (11)