FlyBase Allele Report: Dmel\w[crr]

General Information

Symbol

Dmel\w^crr

Species

D. melanogaster

Name

carrot

FlyBase ID

FBal0018230

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Zachar and Bingham, 1982)

Progenitor genotype

Cytology

Description

Amino acid replacement: H298N. Mutation is within the cytoplasmic ATP binding domain.

(Mackenzie et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

X:2,792,235..2,792,235 [-]

Nucleotide change:

C2792235A

Reported nucleotide change:

C4090A

Amino acid change:

H298N | w-PA

Reported amino acid change:

H298N

(Mackenzie et al., 1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Frolov et al., 2000, Mackenzie et al., 1999)

abnormal eye color | recessive

(Frolov et al., 1998)

visible | recessive

Phenotype Manifest In

pigment cell

(Mackenzie et al., 1999, Frolov et al., 1998, Zachar and Bingham, 1982)

Detailed Description

Statement

Reference

Drosopterin (red pigment) levels are 11% of wild-type levels, xanthommatin levels (brown pigments) are 19% of wild-type levels.

(Mackenzie et al., 1999)

Eye colour: orange-brown.

(Zachar and Bingham, 1982)

Eye colour: reddish brown; no sex difference.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

w^crr has abnormal eye color phenotype, suppressible by ox[+]/ox¹

(Frolov et al., 2000)

w^crr has abnormal eye color | recessive phenotype, suppressible by Rga[+]/Rga⁰³⁸³⁴

(Frolov et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^crr has phenotype, enhanceable by Wow^unspecified

(Bhadra et al., 1998)

w^crr has phenotype, enhanceable by Mow^EMS/Low¹

(Bhadra et al., 1998)

NOT Enhanced by

Statement

Reference

w^crr has phenotype, non-enhanceable by Wow^unspecified/Pcf11^EMS2

(Bhadra et al., 1998)

Suppressed by

Statement

Reference

w^crr has phenotype, suppressible by Low¹/Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Mow^EMS

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Ufo¹

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Ufo¹/Mow^EMS

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Low¹/Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Mow^EMS/Low¹/Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Mow^EMS/Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Mow^EMS/Low¹

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Mow^EMS/Low¹/Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Mow^EMS

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Ufo¹

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Low¹

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Mow^EMS/Pcf11^EMS2

(Bhadra et al., 1998)

w^crr has phenotype, suppressible by Wow^unspecified/Low¹

(Bhadra et al., 1998)

w^crr has pigment cell phenotype, suppressible by RpLP0⁰¹⁵⁴⁴

(Frolov and Birchler, 1998)

w^crr has pigment cell phenotype, suppressible by Rga[+]/Rga⁰³⁸³⁴

(Frolov et al., 1998)

NOT suppressed by

Statement

Reference

w^crr has phenotype, non-suppressible by Wow^unspecified/Pcf11^EMS2

(Bhadra et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

101253

y¹ w^crr

Notes on Origin

Discoverer

Judd, 1962.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

w^crr

Name Synonyms

carrot

Secondary FlyBase IDs

References (9)

Report Sections

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