FB2024_03 , released June 25, 2024
Allele: Dmel\ogre1
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General Information
Symbol
Dmel\ogre1
Species
D. melanogaster
Name
FlyBase ID
FBal0013231
Feature type
allele
Associated gene
Dmel\ogre
Associated Insertion(s)
Carried in Construct
Also Known As
l(1)jnL3
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Lipshitz and Kankel, 1985)
Mutagen
ethyl methanesulfonate
(Nicklas and Cline, 1983)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Watanabe and Kankel, 1990)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous males exhibit a reduction in the size of four ganglion within the optic lobe, the medulla is facing anteriorly and the division of the lobula and lobula plate is not seen.

      (Watanabe and Kankel, 1990)

      Larval/pupal lethal with no escapers at 22oC.

      (Nicklas and Cline, 1983)

      embryonic lethal.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      ogre1 is rescued by ogre+t12.5

      (Watanabe and Kankel, 1990)
      Comments

      Mutant phenotype can be rescued by the introduction of a wild type ogre gene by P element mediated transformation: wild type optic lobe structure is restored. Homozygous lethal phenotype can be rescued by ogre+t12.5 and wild type optic lobe structure is restored in hemizygous males.

      (Watanabe and Kankel, 1990)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Niklas.

      Comments
      Comments

      Maternal germline clonal analysis demonstrates cell lethality in homozygous clones.

      (Perrimon et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      inx1ogrejNL3
      (Spéder and Brand, 2014)
      jnL3
      (Nicklas and Cline, 1983)
      l(1)jnL3
      (Kankel and Lipshitz, 1981)
      l(1)jnl3
      (Lipshitz and Kankel, 1985)
      l(1)ogreljnl3
      (Watanabe and Kankel, 1990)
      ogre1
      (Luedke et al., 2024)
      ogrejnL3
      (Perrimon et al., 1989)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)