FB2024_03 , released June 25, 2024
Allele: Dmel\noc2
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General Information
Symbol
Dmel\noc2
Species
D. melanogaster
Name
FlyBase ID
FBal0013031
Feature type
allele
Associated gene
Dmel\noc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1982, Ashburner et al., 1981)
Progenitor genotype
Caused by aberration
In(2L)noc2
Cytology
Description

-62 to -68. From the molecular map of the wild-type noc-Adh region (McGill, Chia, Karp and Ashburner, 1988); coordinate 0 an EcoRI restriction site 1321 bp to the left of the start of transcription of the larval Adh transcript; '+' values to the right, '-' values to the left.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The post-vertical and ocellar macrochaetae and intra-ocellar microchaetae are disrupted, and the lateral ocelli are reduced in size in noc2/Df(2L)b81a1 flies. The medial ocellus appears normal in these flies.

      (Davis et al., 1997)

      Three ocelli may be present, although they are usually clearly reduced in size compared to wild-type, and may be present just as pigmented "ghosts". Anterior postalar bristles are reduced in number, and the arrangement of the interocellar microchaetae is disturbed. The phenotype is expressed more strongly in late emerging flies, and males are usually affected more than females.

      (Ashburner et al., 1981)

      weak

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      noc2, snaSco-rv1 has viable phenotype

      (Gubb et al., 1985)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      noc2 is an enhancer of chaeta phenotype of snaSco

      (Davis et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Tsubota.

      S. Tsubota.

      (Ashburner et al., 1981)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      noc2
      Name Synonyms
      Secondary FlyBase IDs
        References (9)