FlyBase Allele Report: Dmel\mle[13]

General Information

Symbol

Dmel\mle¹³

Species

D. melanogaster

Name

FlyBase ID

FBal0012346

Feature type

allele

Associated gene

Dmel\mle

Associated Insertion(s)

Carried in Construct

Also Known As

mle^γ286

Key Links

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Kernan et al., 1991)

Progenitor genotype

Cytology

Description

Deletion in mle.

(Kernan et al., 1991)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | male

(Kernan et al., 1991)

lethal | male | recessive

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

mle¹³ is a non-enhancer of phenotype of msl-1^{C.hs.Tag:FLAG}

(Scott et al., 2000)

mle¹³ is a non-enhancer of phenotype of msl-1^{Δ84.Tag:FLAG}

(Scott et al., 2000)

NOT Suppressor of

Statement

Reference

mle¹³ is a non-suppressor of phenotype of msl-1^{Δ84.Tag:FLAG}

(Scott et al., 2000)

mle¹³ is a non-suppressor of phenotype of msl-1^{C.hs.Tag:FLAG}

(Scott et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The addition of msl-2^γ136 to flies containing a single copy of msl-1^{Δ84.T:Zzzz\FLAG} in weak heatshock conditions has no effect on the male viability phenotype seen in these flies. The addition of msl-2^γ136 to flies containing a single copy of msl-1^{C.hs.T:Zzzz\FLAG} in weak heatshock conditions has no effect on the male viability phenotype seen in these flies.

(Scott et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Mutant phenotype can be rescued by P element mediated transformation of a wild type mle gene copy.

(Kernan et al., 1991)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

mle¹³

mle^γ286

(Scott et al., 2000, Kernan et al., 1991)

mle^γ28

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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