FlyBase Allele Report: Dmel\mi[1]

General Information

Symbol

Dmel\mi¹

Species

D. melanogaster

Name

FlyBase ID

FBal0012259

Feature type

allele

Associated gene

Dmel\mi

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Szuplewski et al., 2009)

Progenitor genotype

Cytology

Description

May be an insertion of DNA within the second intron.

(Szuplewski et al., 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate

female sterile

male fertile

visible

visible (with Df(2R)bw-S46)

(Szuplewski et al., 2009)

visible (with mi^SH0818)

(Szuplewski et al., 2009)

visible (with mi^ΔEY22)

(Szuplewski et al., 2009)

Phenotype Manifest In

macrochaeta

macrochaeta & thorax (with Df(2R)bw-S46)

(Szuplewski et al., 2009)

macrochaeta & thorax (with mi^SH0818)

(Szuplewski et al., 2009)

macrochaeta & thorax (with mi^ΔEY22)

(Szuplewski et al., 2009)

microchaeta

Detailed Description

Statement

Reference

mi¹/mi^SH0818 flies show a small bristle phenotype on the adult dorsal thorax, milder than that in mi¹/Df(2R)bw-S46 flies.

mi¹/mi^ΔEY22 flies show a small bristle phenotype on the adult dorsal thorax.

(Szuplewski et al., 2009)

Bristles are almost as small as hairs and hairs are reduced in number and size. Body size is small. Eclosion is delayed. Viability is low and erratic. RK2.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

mi¹/mi^ΔEY22 has visible phenotype, non-enhanceable by Cdk2²/cdc2c[+]

(Szuplewski et al., 2009)

mi¹/mi^ΔEY22 has visible phenotype, non-enhanceable by Cdk2³/cdc2c[+]

(Szuplewski et al., 2009)

Suppressed by

Statement

Reference

mi¹/mi^ΔEY22 has visible phenotype, suppressible by CycE[+]/CycE⁵

(Szuplewski et al., 2009)

mi¹/mi^ΔEY22 has visible phenotype, suppressible by CycE^AR95/CycE[+]

(Szuplewski et al., 2009)

NOT suppressed by

Statement

Reference

mi¹/mi^ΔEY22 has visible phenotype, non-suppressible by Cdk2²/cdc2c[+]

(Szuplewski et al., 2009)

mi¹/mi^ΔEY22 has visible phenotype, non-suppressible by Cdk2³/cdc2c[+]

(Szuplewski et al., 2009)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

mi¹/mi^ΔEY22 has macrochaeta & thorax phenotype, non-enhanceable by Cdk2²/cdc2c[+]

(Szuplewski et al., 2009)

mi¹/mi^ΔEY22 has macrochaeta & thorax phenotype, non-enhanceable by Cdk2³/cdc2c[+]

(Szuplewski et al., 2009)

Suppressed by

Statement

Reference

mi¹/mi^ΔEY22 has macrochaeta & thorax phenotype, suppressible by CycE[+]/CycE⁵

(Szuplewski et al., 2009)

mi¹/mi^ΔEY22 has macrochaeta & thorax phenotype, suppressible by CycE^AR95/CycE[+]

(Szuplewski et al., 2009)

NOT suppressed by

Statement

Reference

mi¹/mi^ΔEY22 has macrochaeta & thorax phenotype, non-suppressible by Cdk2²/cdc2c[+]

(Szuplewski et al., 2009)

mi¹/mi^ΔEY22 has macrochaeta & thorax phenotype, non-suppressible by Cdk2³/cdc2c[+]

(Szuplewski et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygosity for either CycE⁵ or CycE^AR95 suppresses the small bristle phenotype of mi¹/mi^ΔEY22 flies, whereas heterozygosity for cdc2c² or cdc2c³ has no effect.

(Szuplewski et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

3301