FlyBase Allele Report: Dmel\sgl[SG9]

General Information

Symbol

Dmel\sgl^SG9

Species

D. melanogaster

Name

FlyBase ID

FBal0011349

Feature type

allele

Associated gene

Dmel\sgl

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Haerry et al., 1997)

Mutagen

ethyl methanesulfonate

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Haerry et al., 1997)

Phenotype Manifest In

eye-antennal disc

(Haerry et al., 1997)

imaginal disc | larval stage

(Haerry et al., 1997)

imaginal disc | P-stage

(Haerry et al., 1997)

Detailed Description

Statement

Reference

Homozygotes and hemizygotes die during the larval and pupal stages and have small imaginal discs. Homozygotes sometimes give rise to pharate adults. Adult tissues derived from the imaginal discs are reduced and partially differentiated in these pharate adults, while the size of tissues derived from the histoblasts is normal. The eye portion of the third larval instar eye-antennal imaginal disc of sgl^SG9/sgl^A31 flies is smaller than normal.

(Haerry et al., 1997)

imaginal discs small

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

sgl[+]/sgl^SG9 is an enhancer of visible phenotype of dsh⁴, dsh^w

(Haerry et al., 1997)

Phenotype Manifest In

Enhancer of

Statement

Reference

sgl[+]/sgl^SG9 is an enhancer of adult phenotype of dsh⁴, dsh^w

(Haerry et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Dominantly enhances the weak phenotype of dsh⁴/Y flies carrying one copy of dsh^w, increasing the proportion of these flies that have defects in adult structures.

(Haerry et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sgl⁰⁸³¹⁰

(Haerry et al., 1997)

sgl^N71

(Haerry et al., 1997)

sgl^A31

(Haerry et al., 1997)

sgl¹⁰⁵⁰³

(Haerry et al., 1997)

Rescued by

sgl^SG9 is rescued by sgl^Ubi-p63E.PH

(Haerry et al., 1997)

Comments

Homozygotes are generally completely rescued by sgl^Ubi-p63E.PH, although some sgl^Ubi-p63E.PH lines show partial rescue, producing flies with a bat shaped wing and wing margin and vein defects.

(Haerry et al., 1997)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

8984

mwh¹ red¹ e¹ sgl^SG9/TM1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

SG9

(Haerry et al., 1997)

l(3)17m28

l(3)SG9¹

sgl^SG9

ska^SG9

(Haerry et al., 1997)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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