FB2024_03 , released June 25, 2024
Allele: Dmel\Lr
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General Information
Symbol
Dmel\Lr
Species
D. melanogaster
Name
recessive
FlyBase ID
FBal0005892
Feature type
allele
Associated gene
Dmel\L
Associated Insertion(s)
roo{}Lr
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Associated Insertion(s)
roo{}Lr
Cytology
Description

roo insertion in the second intron of the L-RC isoform. In addition, the chromosome also carries a number of other natural transposon insertions in the L region (jockey{}Mohr, opus{}Mohr and roo{}Mohr), however these insertions are found in a number of dominant L mutant alleles isolated around 1920, and also in the ft1 chromosome isolated during the same time period, suggesting that the additional insertions are probably not related to the dominant L mutant eye phenotype.

(Son and Choi, 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygote has small, kidney-shaped eyes. Overlaps wild type at 19o, generally good at 25oC. Heterozygote rarely shows seam or nick. RK2 as homozygote.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Lr has visible | dominant | adult stage phenotype, suppressible by hyxEY06898

      (Zhang et al., 2010)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Lr has eye phenotype, suppressible by hyxEY06898

      (Zhang et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      L.V. Morgan, 23rd Aug. 1929.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Lr
      (Son and Choi, 2020, Zhang et al., 2010, Bischoff et al., 2009)
      Name Synonyms
      recessive
      Secondary FlyBase IDs
        References (4)