FB2024_03 , released June 25, 2024
Allele: Dmel\E(f)1
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General Information
Symbol
Dmel\E(f)1
Species
D. melanogaster
Name
FlyBase ID
FBal0003304
Feature type
allele
Associated gene
E(f)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Belgovsky, 1937)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Belgovsky, 1937)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have abnormal bristles, the phenotype being intermediate between f and Bl. The posterior scutellar bristles are often pale and discoloured. Viability and fertility are poor in homozygotes. Heterozygotes appear wild-type.

      (Belgovsky, 1937)

      Homozygote has short, twisted bristles intermediate between f and Bl mutant phenotype; postscutellars often pale; viability and fertility reduced. Heterozygote is wild type. f1/+;E(f)1/+ slightly more extreme than f1. f1/f1; E(f)1/+ has an extreme forked phenotype and hairs are forked. f1/f1; E(f)1/E(f)1 rarely survives. RK3.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      E(f)1, funspecified has lethal phenotype

      (Belgovsky, 1937)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      E(f)1 is an enhancer of posterior scutellar bristle phenotype of Sbunspecified

      (Belgovsky, 1937)

      E(f)1 is an enhancer of anterior scutellar bristle phenotype of Sbunspecified

      (Belgovsky, 1937)

      E(f)1/E(f)[+] is an enhancer of phenotype of Blunspecified

      (Belgovsky, 1937)

      E(f)1 is an enhancer of phenotype of funspecified

      (Belgovsky, 1937)

      E(f)1 is an enhancer of phenotype of fB27

      E(f)1 is an enhancer of phenotype of f1

      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominantly enhances the Blunspecified, funspecified and Sbunspecified phenotypes. The posterior and sometimes anterior scutellar bristles are hooked, with the hook directed upwards, in E(f)1/+ ; Sbunspecified/+ flies. E(f)1/E(f)1; funspecified/funspecified is almost completely lethal.

      (Belgovsky, 1937)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Belgovsky

      (Belgovsky, 1937)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      E(f)1
      If
      (Belgovsky, 1937)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)