FB2024_03 , released June 25, 2024
Allele: Dmel\aop2
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General Information
Symbol
Dmel\aop2
Species
D. melanogaster
Name
FlyBase ID
FBal0000623
Feature type
allele
Associated gene
Dmel\aop
Associated Insertion(s)
Carried in Construct
Also Known As
aopIIS
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Rogge et al., 1995)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Transheterozygote aop2/aoppok-x8 adult escapers have small rough eyes.

      (Rogge et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      aop[+]/aop2 is an enhancer of ommatidium phenotype of EgfrE1

      (Rogge et al., 1995)
      Suppressor of
      Statement
      Reference

      aop2 is a suppressor of photoreceptor cell R7 phenotype of SosJC2, sev6

      (Rogge et al., 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Has no effect on the eye phenotype produced by activated arm constructs. (either armS44Y.GMR or armS56F.GMR).

      (Freeman and Bienz, 2001)

      sev6/sev+; SosJC2/aop2 exhibit an increase in the number of R7 cells compared to sev6/SosJC2 mutants with two functional aop copies.

      (Rogge et al., 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially complements

      aoppok-x8

      (Rogge et al., 1995)
      Fails to complement

      aope2d

      (Rogge et al., 1995)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      aop-IIs
      (Rogge et al., 1995)
      aop2
      aopII5
      (Gabay et al., 1996)
      aopIIS
      (Smith et al., 2002, O'Keefe et al., 1997, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)