FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2L)let-7-CKO2
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General Information
Symbol
Df(2L)let-7-CKO2
Species
D. melanogaster
Name
FlyBase ID
FBab0047615
Feature type
chromosomal_deletion
Also Known As
let-7-CKO2
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
FLPase
(Wu et al., 2012)
I-SceI
(Wu et al., 2012)
ends-out gene targeting
(Wu et al., 2012)
Class of aberration (relative to wild type)
chromosomal_deletion
(Wu et al., 2012)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wu et al., 2012)
Breakpoints
Causes alleles
lncRNA:let7CKO2
(Wu et al., 2012)
Carries alleles
Transposon Insertions
TI{TI}lncRNA:let7CKO2
(Wu et al., 2012)
Formalized genetic data
Genetic mapping information
Comments

The endogenous let-7-C locus is replaced with w, resulting in deletion of mir-100, let-7 and mir-125.

(Wu et al., 2012)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mir-100
(Wu et al., 2012)
mir-125
(Wu et al., 2012)
mir-let7
(Wu et al., 2012)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

The number of Dl-positive intestinal stem cells per clone and the total number of cells per clone in MARCM clones in the homozygous Df(2L)let-7-CKO2 adult posterior midgut is not significantly different from that of controls.

(Chen et al., 2015)
Stocks (4)
Notes on Origin
Discoverer
 

Generated in parallel with Df(2L)let-7-CGKI and is identical to it except that the endogenous let-7-C locus is replaced with w rather than w and Scer\GAL4.

(Wu et al., 2012)
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Df(2L)let-7-CKO2
let-7-CKO2
(Wu et al., 2020, Chawla et al., 2016, Chen et al., 2015, Wu et al., 2012)
Name Synonyms
Secondary FlyBase IDs
    References (4)