The 2L:4614300..4780032 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of dpy, which published results say is not deleted. The right extent corresponds to the estimated position of the left end of polytene band 25A5, which published cytologies indicate is deleted.
This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).
No effect on In(1)wm4h position-effect variegation.
Heterozygotes with Df(2L)M24F11, Df(2L)M24F-B, Df(2L)tkv2 are lethal and with Df(2L)ed1 or Df(2L)ed2 are viable.
Flies heterozygous for the deletion show a Minute bristle phenotype.
Transheterozygous embryos with Df(2L)tkv2 carrying tkvUbi-p63E.PB die and possess a vri phenotype.
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
Minute phenotype and haplo sterile. Weak head defects, wrinkled dorsal epidermis and internalised and often disorganised filzkorper. Female transheterozygotes with tkv1 are viable and display a wing vein phenotype, some wing vein thickening. Transheterozygotes with tkv4, tkv5 and tkv7 display extremely thickened veins and heterozygotes with tkv6 display wing veins that are very thick and short along the proximal distal axis. Adult Df(2L)tkv3/tkv8 females are very weak, possess atrophic ovaries and do not lay eggs in the few days they survive beyond eclosion. Adult Df(2L)tkv3/tkv7 females lay eggs, embryos from these females crossed to wild type males die showing a moderately ventralised phenotype. Adult Df(2L)tkv3/tkv6 females lay eggs, some of the embryos from these females crossed to wild type males die showing a weakly ventralised phenotype.
Sterile and reduced viability.
Females sterile; males semisterile.
