The P{GMR} vector can act as misexpression element when inserted in the genome, with the GMR regulatory sequences and Hsp70 promoter at the 3' end of the element being able to drive expression out through the P-element 3' end and into neighbouring genomic sequence. However, since it contains Hsp70 3'UTR sequence between the Hsp70 TATA box and the 3'P end and lacks plasmid rescue capability, it is not ideally suited for overexpression screens.
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