l(3)03342
a histone methyltransferase that modifies the lysine 79 residue of histone H3 - necessary for the maintenance phase of Bithorax complex expression - has characteristics of both polycomb- and trithorax-group genes
Please see the JBrowse view of Dmel\gpp for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\gpp using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\gpp in JBrowse3-47.5
3-44.1
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
gpp mutants exhibit phenotypes and genetic interactions that are characteristic of both Polycomb-Group and trithorax-Group genes.
Area matching Drosophila EST AA735819.
A novel trithorax group gene, identified in a genetic screen devised for the isolation of dominant suppressors of pairing-sensitive miniwhite inactivation.
Source for merge of: gpp anon-WO0118547.319
Source for merge of: gpp CG10272 l(3)03342
Source for merge of: gpp CG33324
Source for merge of: CG10272 BcDNA:SD05230
Source for merge of: gpp l(3)S073214b
Annotations CG10272 and CG33324 merged as CG42803 in release 5.30 of the genome annotation.
The 3' exon of release 2 annotation CG10272 (which was deleted in the release 3.1 version of CG10272) has been restored as a distinct annotation, CG33324, in release 3.2 of the genome annotation.
Source for merge of gpp anon-WO0118547.319 was sequence comparison ( date:051113 ).
Source for merge of CG10272 BcDNA:SD05230 was a shared cDNA ( date:030728 ).
The gene is named "grappa" because of the light yellow phenotype associated with the posterior-to-anterior transformation of the A5 and A6 male tergite plates seen in mutants (this light colour reminded one of the authors of a favourite drink from his not so distant youth and thus is the origin of the name).
