l(2)01351, DAIB1, l(2)k05809, l(2)k05802
steroid hormone receptor coactivator - required for border cell migration during oogenesis - links Yorkie to transcriptional control of germline stem cell factors in somatic tissue
Please see the JBrowse view of Dmel\tai for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tai using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\tai in JBrowse2-35
2-30.1
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Identification: in a screen for mutations that cause border cell migration defects in mosaic clones in the ovary.
tai is required cell-autonomously for border cell migration.
Mutations in tai cause defects in migration of border follicle cells in the ovary.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.
The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation. tai gene expression during oogenesis is not critical to embryonic development, but the gene function may be essential for fertilisation and/or completion of meiosis.
Source for merge of: tai l(2)k05809 l(2)01351 l(2)k05802
Source for merge of: tai NEST:bs13g05
Source for merge of: tai CG13109 CG18494
Source for merge of tai CG13109 CG18494 was sequence comparison ( date:001007 ).
Source for identity of: tai Aib1
The gene is named "taiman", meaning "too slow" (border cell migration is affected in mutants).
