DLK, drosokinin, kinin, pp, LCK
Please see the JBrowse view of Dmel\Lk for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Lk using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Lk is expressed in MNBp in embryos in the labial segment and in segments T1-A7.
Comment: author refers to embryonic stage 18
Lk is expressed in three to four neurons in the lateral protocerebrum of larval brains, named as the ALK neurons. Lk is expressed in a second group of neurons called the LHLK cells located on the lateral horn in adults and an equivalent position in larvae. Lk is expressed in the SELK neurons, which are present in group sof two or three pairs in the subesophageal ganglion. Seven pairs of abdominal neurons, called the LK cells, express Lk.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Lk in JBrowse3-42
3-36.3
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The Leucokinin peptide raises both fluid secretion rates and intracellular Ca2+ concentration in Malpighian tubules in vitro.
Source for merge of: Leucokinin CG13480