FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: MITOCHONDRIAL COMPLEX IV - TESTIS-SPECIFIC VARIANT
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General Information
Name
MITOCHONDRIAL COMPLEX IV - TESTIS-SPECIFIC VARIANT
Species
D. melanogaster
Symbol
MCIV-T
FlyBase ID
FBgg0001840
Date last reviewed
2023-04-03
Number of members
15
Description
Description
Cytochrome c oxidase (COX) is the terminal complex (complex IV) of the electron transfer chain, embedded in the mitochondrial inner membrane. It catalyzes electron transfer from reduced cytochrome c to molecular oxygen in a process coupled to the transfer of protons across the inner membrane, thus contributing to the generation of the proton gradient that is used by ATP synthase to drive ATP synthesis. (Adapted from PMID:17091399 and PMID:28870773.)
Notes on Group
Source Material
The MITOCHONDRIAL COMPLEX IV - TESTIS-SPECIFIC VARIANT Gene Group has been compiled using the following publication(s): Brischigliaro et al., 2022, Marygold, 2021.2.26, Tripoli et al., 2005, and Szuplewski and Terracol, 2001 .
Key Gene Ontology (GO) terms
Molecular Function
cytochrome-c oxidase activity
Biological Process
mitochondrial electron transport, cytochrome c to oxygen
Cellular Component
mitochondrial respiratory chain complex IV
Enzymatic activity
Enzyme name (EC)
cytochrome-c oxidase (7.1.1.9)
Related Gene Groups
Parent group(s)
MITOCHONDRIAL OXPHOS COMPLEX VARIANTS
Other related group(s)
MITOCHONDRIAL COMPLEX IV SUBUNITS
Members (15)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
COX4L
Cytochrome c oxidase subunit 4-like
cytochrome c oxidase
(Tripoli et al., 2005, Szuplewski and Terracol, 2001)
COX5A
Cytochrome c oxidase subunit 5A
CoVa, cytochrome c oxidase subunit Va, tend, Va, tenured
(Brischigliaro et al., 2022, Tripoli et al., 2005, Szuplewski and Terracol, 2001)
COX5BL
Cytochrome c oxidase subunit 5B-like
(Tripoli et al., 2005, Szuplewski and Terracol, 2001)
COX6AL
Cytochrome c oxidase subunit 6A-like
(Tripoli et al., 2005)
COX6AL2
Cytochrome c oxidase subunit 6A-like 2
(Szuplewski and Terracol, 2001)
COX6B
Cytochrome c oxidase subunit 6B
CoVIb, Cytochrome c oxidase subunit VIb
(Brischigliaro et al., 2022, Tripoli et al., 2005, Szuplewski and Terracol, 2001)
COX6CL
Cytochrome c oxidase subunit 6C-like
(Marygold, 2021.2.26)
COX7AL
Cytochrome c oxidase subunit 7A-like
(Brischigliaro et al., 2022, Tripoli et al., 2005, Szuplewski and Terracol, 2001)
COX7B
Cytochrome c oxidase subunit 7B
(Brischigliaro et al., 2022)
COX7CL
Cytochrome c oxidase subunit 7C-like
(Marygold, 2021.2.26)
COX8
Cytochrome c oxidase subunit 8
0554/18, VIII, CoVIII
(Brischigliaro et al., 2022, Szuplewski and Terracol, 2001)
mt:CoI
mitochondrial Cytochrome c oxidase subunit I
COI, COXI, COX1, cytochrome c oxidase subunit I, COX
(Brischigliaro et al., 2022, Szuplewski and Terracol, 2001)
mt:CoII
mitochondrial Cytochrome c oxidase subunit II
COII, COXII, Cox2, COX, cytochrome c
(Brischigliaro et al., 2022, Szuplewski and Terracol, 2001)
mt:CoIII
mitochondrial Cytochrome c oxidase subunit III
COIII, COXIII, COX3, cytochrome c oxidase subunit III, COX
(Brischigliaro et al., 2022, Szuplewski and Terracol, 2001)
ND-MLRQ
NADH dehydrogenase (ubiquinone) MLRQ subunit
(Brischigliaro et al., 2022, Tripoli et al., 2005)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
MCIV-T
Cytochrome c oxidase
MITOCHONDRIAL COMPLEX IV - TESTIS-SPECIFIC VARIANT
COX
Secondary FlyBase ID(s)
References (5)