The PAR complex is an evolutionarily conserved ternary protein kinase complex that plays an important role in the regulation of cell polarity required for asymmetric cleavage of many cell types. (Adapted from FBrf0238574 and FBrf0210666).
Notes on Group
aPKC is the active component of the PAR complex which regulates the activities of other proteins functioning downstream in the cell polarity pathway by phosphorylation. (FBrf0209133).
