FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term PAR polarity complex ID (Ontology) GO:0120157 (Gene Ontology)
Definition A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.[ PubMed:11113154 PubMed:18005931 PubMed:22500799 PubMed:28682236 ]
Also Known As "apical polarity complex"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
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 Gene Groups Genes
 PAR polarity complex (all annotations which use CV term, excluding "NOT" statements)       1      3
     part_of | PAR polarity complex       --       3
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  protein kinase complex
   |__serine/threonine protein kinase complex
       |__PAR polarity complex  4 rec.
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Is a serine/threonine protein kinase complex
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Synonyms
  • "apical polarity complex" EXACT
    "BEM1-CDC24-CLA4 complex" NARROW
    "Cdc42p GEF-PAK complex" NARROW
    "PAR3-PAR6-atypical PKC" NARROW
    "PAR3/PAR6/aPKC" NARROW
    "PAR6-PAR3-aPKC complex" NARROW[ PubMed:18005931 ]
Secondary IDs
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