FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: SCRIBBLE COMPLEX
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General Information
Name
SCRIBBLE COMPLEX
Species
D. melanogaster
Symbol
SCRIBC
FlyBase ID
FBgg0001762
Date last reviewed
2022-11-02
Number of members
3
Description
Description
The scribble complex is the basolateral polarity complex that localizes to the adherens junction and regulate cell polarity. Scribble complex works with the PAR and Crumbs polarity complexes to regulate apicobasal polarity and asymmetry in cells. (Adapted from FBrf0246382 and FBrf0220779).
Notes on Group
Source Material
The SCRIBBLE COMPLEX Gene Group has been compiled using the following publication(s): Khoury and Bilder, 2020 and Ventura et al., 2020 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
establishment or maintenance of cell polarity
Cellular Component
Related Gene Groups
Protein Complex group(s)
CRUMBS COMPLEX
PAR COMPLEX
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
dlg1
discs large 1
Dlg, Discs large, Discs-large, Disc large, l(1)d.lg-1
(Khoury and Bilder, 2020, Ventura et al., 2020)
l(2)gl
lethal (2) giant larvae
lgl, lethal giant larvae, p127, dlgl, p127l(2)gl
(Khoury and Bilder, 2020, Ventura et al., 2020)
scrib
scribble
scribbled, smi97B, scrb, ird15, l(3)j7B3
(Khoury and Bilder, 2020, Ventura et al., 2020)
External Data
Synonyms and Secondary IDs
Synonym(s)
SCRIBC
SCRIBBLE COMPLEX
Scrib-Dlg complex
Scribble cell polarity complex
Secondary FlyBase ID(s)
References (3)