FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: siRNA RISC-LOADING COMPLEX
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General Information
Name
siRNA RISC-LOADING COMPLEX
Species
D. melanogaster
Symbol
siRLC
FlyBase ID
FBgg0001552
Date last reviewed
Number of members
3
Description
Description
The siRNA-RISC loading complex binds siRNAs and loads it onto AGO2 to form an RNA-induced silencing complex (RISC). (Adapted from FBrf0237457.)
Notes on Group
Source Material
The siRNA RISC-LOADING COMPLEX Gene Group has been compiled using the following publication(s): Tomari et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
RISC complex assembly
Cellular Component
RISC-loading complex
Related Gene Groups
Parent group(s)
RISC LOADING COMPLEXES
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
AGO2
Argonaute 2
Ago-2, dAgo2, Argonaute, DmAgo2
(Tomari et al., 2007)
Dcr-2
Dicer-2
Dcr2, Dicer, dmDcr-2, dcr
(Tomari et al., 2007)
r2d2
r2d2
(Tomari et al., 2007)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
siRLC
siRNA RISC-LOADING COMPLEX
Short interfering RNA-RNA-induced silencing complex loading complex
Secondary FlyBase ID(s)
References (2)