A deletion and an amino acid change within the second exon of myd.
G19190547T
E156D | myd-PA; E156D | myd-PB
myd3PM71 dominantly leads to a progressive decrease in flight ability, with myd3PM71/Df(3R)ED5938, myd3PM71/mydMB03509 and myd3PM71/mydMI08666 transheterozygotes showing a similar progressive decrease in flight ability.
myd3PM71 mutants DLM neurons show increased apoptosis (TUNEL-positive cell bodies in the adult thoracic ganglia) neuromuscular junctions show progressive decreases in branch number and length, as well as in bouton number. Their nuclear
myd3PM71/myd3PM71 mutants expressing mydUAS.Venus under the control of either Scer\GAL4αTub84B.PL alone, or Scer\GAL4Mhc.PK and Scer\GAL4VGlut-OK371 combined show DLM neuromuscular junctions with increased branch number and length, as well as increased bouton number. myd3PM71/myd3PM71 mutants expressing mydUAS.Venus under the control of Scer\GAL4Mhc.PK alone show DLM neuromuscular junctions with increased branch number and length.
myd3PM71 has abnormal flight phenotype, suppressible by tkvCA.UAS/Scer\GAL4VGlut-OK371
myd3PM71 has abnormal neuroanatomy | adult stage | progressive phenotype, suppressible | partially by Hsap\SDF4UAS.cSa/Scer\GAL4αTub84B.PL
myd3PM71 has abnormal neuroanatomy | adult stage | progressive phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Scer\GAL4VGlut-OK371/Hsap\SDF4UAS.cSa
myd3PM71 has abnormal neuroanatomy | adult stage | progressive phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Hsap\SDF4UAS.cSa
myd3PM71 has abnormal flight | dominant | progressive phenotype, suppressible | partially by Hsap\SDF4UAS.cSa/Scer\GAL4αTub84B.PL
myd3PM71 has abnormal flight | dominant | progressive phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Scer\GAL4VGlut-OK371/Hsap\SDF4UAS.cSa
myd3PM71 has abnormal flight | dominant | progressive phenotype, non-suppressible by Scer\GAL4Mhc.PK/Hsap\SDF4UAS.cSa
Mad1-2, myd[+]/myd3PM71 has abnormal flight phenotype
gbbD20, myd[+]/myd3PM71 has abnormal flight phenotype
myd[+]/myd3PM71, tkv7 has abnormal flight phenotype
myd[+]/myd3PM71, tkv8 has abnormal flight phenotype
myd[+]/myd3PM71, witB11 has abnormal flight phenotype
Hsap\SDF4UAS.cSa, Scer\GAL4αTub84B.PL, myd3PM71 has abnormal neuroanatomy | adult stage phenotype
Hsap\SDF4UAS.cSa, Scer\GAL4Mhc.PK, Scer\GAL4VGlut-OK371, myd3PM71 has abnormal neuroanatomy | adult stage phenotype
Hsap\SDF4UAS.cSa, Scer\GAL4Mhc.PK, myd3PM71 has abnormal neuroanatomy | adult stage phenotype
myd3PM71 has adult neuromuscular junction phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Scer\GAL4VGlut-OK371/Hsap\SDF4UAS.cSa
myd3PM71 has NMJ bouton | adult stage | decreased number phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Scer\GAL4VGlut-OK371/Hsap\SDF4UAS.cSa
myd3PM71 has adult neuromuscular junction phenotype, suppressible | partially by Hsap\SDF4UAS.cSa/Scer\GAL4αTub84B.PL
myd3PM71 has adult neuromuscular junction phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Hsap\SDF4UAS.cSa
myd3PM71 has NMJ bouton | adult stage | decreased number phenotype, suppressible | partially by Hsap\SDF4UAS.cSa/Scer\GAL4αTub84B.PL
myd3PM71 has NMJ bouton | adult stage | decreased number phenotype, suppressible | partially by Scer\GAL4Mhc.PK/Hsap\SDF4UAS.cSa
myd3PM71/myd3PM71 mutants expressing Hsap\SDF4UAS.cSa under the control of either Scer\GAL4αTub84B.PL or Scer\GAL4Mhc.PK and Scer\GAL4VGlut-OK371 combined show DLM neuromuscular junctions with increased branch number and length, as well as increased bouton number.
myd3PM71 is rescued by mydUAS.Venus/Scer\GAL4Mhc.PK/Scer\GAL4VGlut-OK371
myd3PM71 is rescued by mydUAS.Venus/Scer\GAL4αTub84B.PL
myd3PM71 is partially rescued by mydUAS.Venus/Scer\GAL4Mhc.PK