UASt regulatory sequences drive expression of a cDNA that encodes Hsap\MARK4, mutated to carry a double mutation (deletion of residue Gly316 and an E317D amino acid replacement) that is associated with an elevated risk of early-onset Alzheimer disease.
Hsap\MARK4ΔG316E317D.UAS, Scer\GAL4GMR.PU is an enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\MAPTS2A.UAS.0N4R, Scer\GAL4GMR.PU
Hsap\MARK4ΔG316E317D.UAS, Scer\GAL4GMR.PU is an enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4GMR.PU
Hsap\MARK4ΔG316E317D.UAS, Scer\GAL4GMR.PU is an enhancer of lamina | adult stage phenotype of Hsap\MAPTS2A.UAS.0N4R, Scer\GAL4GMR.PU
Hsap\MARK4ΔG316E317D.UAS, Scer\GAL4GMR.PU is an enhancer of lamina | adult stage phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4GMR.PU