FlyBase Allele Report: Dmel\mbt[+tPa]

General Information

Symbol

Dmel\mbt^+tPa

Species

D. melanogaster

Name

FlyBase ID

FBal0347548

Feature type

allele

Associated gene

Dmel\mbt

Associated Insertion(s)

Carried in Construct

P{mbt.gen}

Also Known As

P[gen-mbt]

Key Links

Genomic Maps

JBrowse

Transgenic product class

genomic_DNA

(Pütz, 2019)

wild_type

(Pütz, 2019)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Pütz, 2019)

wild_type

(Pütz, 2019)

Mutagen

in vitro construct

(Pütz, 2019)

Progenitor genotype

Carried in construct

P{mbt.gen}

Cytology

Description

Genomic EcoRI fragment that encompasses mbt; extends from 1410bp upstream of the translation start site to 3526bp downstream of the stop codon.

(Pütz, 2019)

Allele components

Component

Use(s)

Regulatory region(s)

mbt

Encoded product / tool

mbt

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

rescue_region

X:16,609,782..16,617,539 [+]

Comment:

Genomic rescue fragment reported to extend from 1410bp upstream of the translation start site to 3526bp downstream of the stop codon.

(Pütz, 2019)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

mbt^+tPa/mbt[+] is a suppressor of abnormal neuroanatomy | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src64B^UAS.cCa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of abnormal cell adhesion | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src64B^UAS.cCa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of abnormal size | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src64B^UAS.cCa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of abnormal neuroanatomy | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src42A^UAS.cPa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of abnormal cell adhesion | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src42A^UAS.cPa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of abnormal size | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src42A^UAS.cPa

(Pütz, 2019)

Phenotype Manifest In

Suppressor of

Statement

Reference

mbt^+tPa/mbt[+] is a suppressor of photoreceptor R4 precursor cell | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src42A^UAS.cPa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of adherens junction | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src42A^UAS.cPa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of photoreceptor R3 precursor cell | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src64B^UAS.cCa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of photoreceptor R4 precursor cell | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src64B^UAS.cCa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of adherens junction | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src64B^UAS.cCa

(Pütz, 2019)

mbt^+tPa/mbt[+] is a suppressor of photoreceptor R3 precursor cell | wandering third instar larval stage phenotype of Scer\GAL4^GMR.PF, Src42A^UAS.cPa

(Pütz, 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

mbt^+tPa rescues mbt^P1

(Pütz et al., 2021)

mbt^+tPa rescues mbt^P1

(Pütz, 2019)

Comments

mbt^+tPa rescues the shortened adherens junction phenotype between photoreceptor precursor cells R3 and R4 and between R2 and R5 in row 5 ommatidia of mbt^P1/mbt^P1 wandering third instar larvae.

(Pütz, 2019)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mbt^+tPa

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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