FlyBase Allele Report: Scer\GAL4[oc.1.6]

General Information

Symbol

Scer\GAL4^oc.1.6

Species

S. cerevisiae

Name

FlyBase ID

FBal0328180

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{oc-GAL4.1.6}

Also Known As

otd-Gal4, otd^1.6-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(McDonald et al., 2010, Morante and Desplan, 2008)

Progenitor genotype

Carried in construct

P{oc-GAL4.1.6}

Cytology

Description

A 1.6kb enhancer fragment from the oc third intron regulates expression of a GAL4 driver.

(McDonald et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

wandering third instar larval stage -- adult stage

photoreceptor neuron

(McDonald et al., 2010)

eye photoreceptor cell

(Jukam et al., 2013)

adult stage

transmedullary neuron Tm2

(Ting et al., 2014, Takemura et al., 2011, Morante and Desplan, 2008)

Additional Information

Statement

Reference

ScerGAL4^oc.1.6 drives expression in photoreceptor cells; expression initiates shortly after completion of photoreceptor specification in late third larval instar larvae, and is maintained throughout photoreceptor development.

(McDonald et al., 2010)

Marker for

transmedullary neuron Tm2

(Ting et al., 2014, Takemura et al., 2011, Morante and Desplan, 2008)

Reflects expression of

(Ting et al., 2014, Jukam et al., 2013, Takemura et al., 2011, McDonald et al., 2010, Morante and Desplan, 2008)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology, with CarT^KK104029

(Stenesen et al., 2015)

Phenotype Manifest In

photoreceptor, with Kr-h1^UAS.cFa

(Fichelson et al., 2012)

photoreceptor, with oc^uvi

(Fichelson et al., 2012)

rhabdomere, with oc^uvi

(Fichelson et al., 2012)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^oc.1.6/Lasp^L.UASp is a suppressor of grandchildless | dominant phenotype of Lasp^y41/Lasp^y45, osk¹

(Suyama et al., 2009)

NOT Suppressor of

Statement

Reference

Scer\GAL4^oc.1.6/Lasp^WA.UASp is a non-suppressor of grandchildless | dominant phenotype of Lasp^y41/Lasp^y45, osk¹

(Suyama et al., 2009)

Lasp^S.UASp/Scer\GAL4^oc.1.6 is a non-suppressor of grandchildless | dominant phenotype of Lasp^y41/Lasp^y45, osk¹

(Suyama et al., 2009)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^oc.1.6, oc^uvi has photoreceptor phenotype, suppressible | partially by Kr-h1^KK112003, Scer\GAL4^oc.1.6

(Fichelson et al., 2012)

Scer\GAL4^oc.1.6, oc^uvi has rhabdomere phenotype, suppressible | partially by Kr-h1^KK112003, Scer\GAL4^oc.1.6

(Fichelson et al., 2012)

Scer\GAL4^oc.1.6, oc^uvi has photoreceptor phenotype, suppressible | partially by Kr-h1^GD4367, Scer\GAL4^oc.1.6

(Fichelson et al., 2012)

Scer\GAL4^oc.1.6, oc^uvi has rhabdomere phenotype, suppressible | partially by Kr-h1^GD4367, Scer\GAL4^oc.1.6

(Fichelson et al., 2012)

Suppressor of

Statement

Reference

Kr-h1^KK112003, Scer\GAL4^oc.1.6 is a suppressor | partially of photoreceptor phenotype of Scer\GAL4^oc.1.6, oc^uvi

(Fichelson et al., 2012)

Kr-h1^KK112003, Scer\GAL4^oc.1.6 is a suppressor | partially of rhabdomere phenotype of Scer\GAL4^oc.1.6, oc^uvi

(Fichelson et al., 2012)

Kr-h1^GD4367, Scer\GAL4^oc.1.6 is a suppressor | partially of photoreceptor phenotype of Scer\GAL4^oc.1.6, oc^uvi

(Fichelson et al., 2012)

Kr-h1^GD4367, Scer\GAL4^oc.1.6 is a suppressor | partially of rhabdomere phenotype of Scer\GAL4^oc.1.6, oc^uvi

(Fichelson et al., 2012)

Hsap\OTX1^UAS.Tag:FLAG/Scer\GAL4^oc.1.6 is a suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\OTX1^UAS.Tag:FLAG/Scer\GAL4^oc.1.6 is a suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Hsap\OTX2^UAS.Tag:FLAG is a suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Hsap\OTX2^UAS.Tag:FLAG is a suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\CRX^UAS.Tag:FLAG/Scer\GAL4^oc.1.6 is a suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\CRX^UAS.Tag:FLAG/Scer\GAL4^oc.1.6 is a suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\CRX^{R90W.UAS.Tag:FLAG}/Scer\GAL4^oc.1.6 is a suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\CRX^{R90W.UAS.Tag:FLAG}/Scer\GAL4^oc.1.6 is a suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\CRX^{I138fs48.UAS.Tag:FLAG}/Scer\GAL4^oc.1.6 is a suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Hsap\CRX^{I138fs48.UAS.Tag:FLAG}/Scer\GAL4^oc.1.6 is a suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Hsap\CRX^{E80A.UAS.Tag:FLAG} is a suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Hsap\CRX^{E80A.UAS.Tag:FLAG} is a suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Lasp^L.UASp is a suppressor of primordial germ cell | embryonic stage 11 phenotype of Lasp^y41/Lasp^y45, osk¹

(Suyama et al., 2009)

NOT Suppressor of

Statement

Reference

Scer\GAL4^oc.1.6/Hsap\CRX^{K88N.UAS.Tag:FLAG} is a non-suppressor of rhabdomere phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Hsap\CRX^{K88N.UAS.Tag:FLAG} is a non-suppressor of ommatidium phenotype of oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/Lasp^WA.UASp is a non-suppressor of primordial germ cell | embryonic stage 11 phenotype of Lasp^y41/Lasp^y45, osk¹

(Suyama et al., 2009)

Lasp^S.UASp/Scer\GAL4^oc.1.6 is a non-suppressor of primordial germ cell | embryonic stage 11 phenotype of Lasp^y41/Lasp^y45, osk¹

(Suyama et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^oc.1.6/Nlg4^UAS.cLa rescues Nlg4^KO10

(Liu et al., 2017)

Scer\GAL4^oc.1.6/oc^UAS.Tag:FLAG rescues oc^uvi

(Terrell et al., 2012)

Scer\GAL4^oc.1.6/oc^UAS.FL rescues oc^uvi

(McDonald et al., 2010)

Scer\GAL4^oc.1.6/oc^ΔN.UAS rescues oc^uvi

(McDonald et al., 2010)

Partially rescues

Scer\GAL4^oc.1.6/oc^ΔAB.UAS partially rescues oc^uvi

(McDonald et al., 2010)

oc^ΔC.UAS/Scer\GAL4^oc.1.6 partially rescues oc^uvi

(McDonald et al., 2010)

oc^ΔNC.UAS/Scer\GAL4^oc.1.6 partially rescues oc^uvi

(McDonald et al., 2010)

Scer\GAL4^oc.1.6/oc^ΔA.UAS partially rescues oc^uvi

(McDonald et al., 2010)

Scer\GAL4^oc.1.6/oc^ΔB.UAS partially rescues oc^uvi

(McDonald et al., 2010)

oc^ΔABC.UAS/Scer\GAL4^oc.1.6 partially rescues oc^uvi

(McDonald et al., 2010)

Scer\GAL4^oc.1.6/oc^HD.UAS partially rescues oc^uvi

(McDonald et al., 2010)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Scer\GAL4^oc.1.6

Scer\GAL4^oc.PC

Scer\GAL4^otd

Name Synonyms

ocelliless promoter construct of Cook

Secondary FlyBase IDs

FBal0268464
FBal0218174

References (19)

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