UAS regulatory sequences drive expression of a Hsap\ALKAL1 cDNA.
Expressing Hsap\ALKAL1UAS.cGa under the control of Scer\GAL4GMR.PF has no impact on eye phenotype.
Expression of Hsap\ALKAL1Scer\UAS.cGa under the control of Scer\GAL4GMR.PF does not induce any obvious eye morphological phenotype in adult flies.
Drer\ltkUAS.cFa, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has visible | adult stage | temperature conditional phenotype
Drer\ltkUAS.cFa, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has increased mortality | temperature conditional phenotype
Hsap\ALKUAS.cSa, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has visible | adult stage phenotype
Hsap\ALKUAS.cSa, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has some die during pupal stage phenotype
Hsap\ALKL1198F.UAS, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has visible | adult stage phenotype
Hsap\ALKG1201E.UAS, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has visible | adult stage phenotype
Drer\ltkUAS.cFa, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has eye | temperature conditional phenotype
Hsap\ALKUAS.cSa, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has eye phenotype
Hsap\ALKL1198F.UAS, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has eye phenotype
Hsap\ALKG1201E.UAS, Hsap\ALKAL1UAS.cGa, Scer\GAL4GMR.PF has eye phenotype
Simultaneous expression of either Hsap\ALKScer\UAS.cSa or Hsap\ALKL1198F.Scer\UAS with Hsap\ALKAL1Scer\UAS.cGa under the control of Scer\GAL4GMR.PF leads to a severe eye degeneration phenotype in adult flies along with increased pupal lethality, co-expression of Hsap\ALKAL1Scer\UAS.cGa with Hsap\ALKG1201E.Scer\UAS results in a strong rough eye phenotype, whereas co-expression with or Hsap\ALKI1250T.Scer\UAS does not induce any obvious eye defects.