FB2024_03 , released June 25, 2024
Allele: Dmel\Rgk1ΔN.UAS.B.GFP
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General Information
Symbol
Dmel\Rgk1ΔN.UAS.B.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0326525
Feature type
allele
Associated gene
Dmel\Rgk1
Associated Insertion(s)
Carried in Construct
P{UAS-Rgk1.ΔN.B.GFP}
Key Links
Transgenic product class
inframe_deletion
(Murakami et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Murakami et al., 2017)
Mutagen
in vitro construct
(Murakami et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Rgk1.ΔN.B.GFP}
Cytology
Description

UAS regulatory sequences drive expression of the RB isoform of Rgk1 with deletion of amino acids 161-797 (including the DUF2967 domain), fused with GFP on the N-terminal.

(Murakami et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Rgk1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The co-expression of Rgk1ΔN.Scer\UAS.B.T:Avic\GFP partially suppresses the intermediate-term olfactory memory defects observed upon the expression of Rac1V12.Scer\UAS under the control of Scer\GAL4ey-OK107 only during adulthood (by using Gal80[ts]).

      (Murakami et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4ey-OK107/Rgk1ΔN.UAS.B.GFP partially rescues Rgk1Δ

      (Murakami et al., 2017)
      Comments

      The expression of Rgk1ΔN.Scer\UAS.B.T:Avic\GFP under the control of Scer\GAL4ey-OK107 rescues the intermediate-term olfactory memory defects observed in Rgk1Δ homozygotes, and even leads to a small increase in intermediate-term memory performance, as compared to controls; this rescue does not occurs if individuals are subjected to cold-shock anesthesia after conditioning.

      (Murakami et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rgk1ΔN.Scer\UAS.B.T:Avic\GFP
      Rgk1ΔN.UAS.B.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)