FB2024_03 , released June 25, 2024
Allele: Hsap\TNPO1UAS.cJa
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General Information
Symbol
Hsap\TNPO1UAS.cJa
Species
H. sapiens
Name
Saccharomyces cerevisiae UAS construct a of Jackel
FlyBase ID
FBal0324824
Feature type
allele
Associated gene
Hsap\TNPO1
Associated Insertion(s)
Carried in Construct
P{UAS-hTNPO1.J}
Key Links
Transgenic product class
wild_type
(Jäckel et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Jäckel et al., 2015)
Mutagen
in vitro construct
(Jäckel et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-hTNPO1.J}
Cytology
Description

UAS regulatory sequences drive expression of Hsap\TNPO1.

(Jäckel et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\TNPO1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Hsap\TNPO1Scer\UAS.cJa under the control of Scer\GAL4GMR.PF does not have obvious effects on the eye, as compared to controls.

      (Jäckel et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The co-expression of Hsap\TNPO1Scer\UAS.cJa strongly ameliorates the severe eye defects resulting from the Scer\GAL4GMR.PF-driven expression of either Hsap\FUSScer\UAS.cJa.T:Ivir\HA1 alone or Hsap\FUSScer\UAS.cJa.T:Ivir\HA1 together with TrnGD33, as compared to the expression of a control UAS-regulated transgene.

      (Jäckel et al., 2015)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\TNPO1Scer\UAS.cJa
      Hsap\TNPO1UAS.cJa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Jackel
      Secondary FlyBase IDs
        References (1)