FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Tmc-Gal4
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General Information
Symbol
Scer\GAL4Tmc-Gal4
Species
S. cerevisiae
Name
FlyBase ID
FBal0321091
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
TI{GAL4}TmcGal4
Carried in Construct
Also Known As
tmcGAL4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-out gene targeting
(Guo et al., 2016)
Progenitor genotype
Associated Insertion(s)
TI{GAL4}TmcGal4
Cytology
Description

Sequence encoding a GAL4 driver and a w+* marker are inserted into the Tmc locus near the translation initiation codon of Tmc isoform PD, resulting in about 7,000 bp of the Tmc gene being replaced by the reporter construct and more than 1,000 amino acids (about one-half of the coding sequence) of Tmc being deleted.

(Guo et al., 2016)
Allele components
Component
Use(s)
Inserted element
TI{GAL4}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Hsap\KCNJ2IVS.10xUAS.EGFP) of Scer\GAL4Tmc-Gal4 cells in adult females does not affect preference for softer 100 mM sucrose-containing agarose for egg laying, compared to controls.

      (Wu et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4Tmc-Gal4
      tmcGAL4
      (Wu et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)