FB2024_03 , released June 25, 2024
Allele: Dmel\foiUAS.cCa
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General Information
Symbol
Dmel\foiUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Carrasco-Rando
FlyBase ID
FBal0319774
Feature type
allele
Associated gene
Dmel\foi
Associated Insertion(s)
Carried in Construct
P{UAS-foi.C}
Key Links
Transgenic product class
cDNA
(Carrasco-Rando et al., 2016)
wild_type
(Carrasco-Rando et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Carrasco-Rando et al., 2016)
wild_type
(Carrasco-Rando et al., 2016)
Mutagen
in vitro construct
(Carrasco-Rando et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-foi.C}
Cytology
Description

UASt regulatory sequences drive expression of the full-length foi RE41071 cDNA.

(Carrasco-Rando et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
foi
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of foiScer\UAS.cCa under the control of Scer\GAL4Mef2.PU has no effect on muscle patterning in embryos.

      (Carrasco-Rando et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      foiUAS.cCa/Scer\GAL4Mef2.PU rescues foiC153

      (Carrasco-Rando et al., 2016)

      foiUAS.cCa/Scer\GAL4Mef2.PU rescues foiC887

      (Carrasco-Rando et al., 2016)
      Partially rescues

      Scer\GAL4sns.PU/foiUAS.cCa partially rescues foiC887

      (Carrasco-Rando et al., 2016)

      foiUAS.cCa/Scer\GAL4kirre.PU partially rescues foiC887

      (Carrasco-Rando et al., 2016)

      foiUAS.cCa partially rescues foiC887

      (Carrasco-Rando et al., 2016)
      Comments

      Expression of foiScer\UAS.cCa under the control of Scer\GAL4Mef2.PU fully rescues the muscle patterning and fusion, visceral mesoderm, and defective fusion-competent myoblast differentiation phenotypes of foiC153/foiC153 and foiC887/foiC887 mutants.

      Expression of foiScer\UAS.cCa under the control of Scer\GAL4sns.PU partially rescues the defective fusion-competent myoblast differentiation and DA1 fusion phenotypes of foiC887/foiC887 mutants.

      Expression of foiScer\UAS.cCa under the control of Scer\GAL4kirre.PU fails to rescue the defective fusion-competent myoblast differentiation, but does rescue the muscle patterning defects of foiC887/foiC887 mutants.

      Expression of foiScer\UAS.cCa with no GAL4 driver is sufficient to reduce the defective fusion-competent myoblast differentiation phenotype, and partially rescue the DA1 fusion phenotype of foiC887/foiC887 mutants.

      (Carrasco-Rando et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      foiScer\UAS.cCa
      foiUAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Carrasco-Rando
      Secondary FlyBase IDs
        References (1)