FB2024_03 , released June 25, 2024
Allele: Dmel\cycEGFP
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General Information
Symbol
Dmel\cycEGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0319047
Feature type
allele
Associated gene
Dmel\cyc
Associated Insertion(s)
Carried in Construct
P{GFP-cyc}
Key Links
Transgenic product class
genomic_DNA
(Liu et al., 2015)
wild_type
(Liu et al., 2015)
Mutagen
    Nature of the Allele
    Transgenic product class
    genomic_DNA
    (Liu et al., 2015)
    wild_type
    (Liu et al., 2015)
    Mutagen
    Progenitor genotype
    Carried in construct
    P{GFP-cyc}
    Cytology
    Description

    Genomic fragment (BAC-PAC clone C322-08N23) which contains cyc. A EGFP tag has been inserted at the N-terminal end of the cyc open reading frame.

    (Liu et al., 2015)
    Allele components
    Component
    Use(s)
    Regulatory region(s)
    cyc
    Encoded product / tool
    cyc
    Tagged with
    EGFP
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter or direct label
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        third instar larval stage
        adult LP neuron
        (Liu et al., 2015)
        larval s-LNv Pdf neuron
        (Liu et al., 2015)
        larval LNd neuron
        (Liu et al., 2015)
        larval DN period neuron
        (Liu et al., 2015)
        adult stage
        adult LP neuron
        (Liu et al., 2015)
        LNv neuron
        (Liu et al., 2015)
        adult s-LNv neuron
        (Liu et al., 2015)
        LNd neuron
        (Liu et al., 2015)
        DN1 neuron
        (Liu et al., 2015)
        DN2 neuron
        (Liu et al., 2015)
        DN3 neuron
        (Liu et al., 2015)
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        cyc
        (Liu et al., 2015)
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Partially rescues

        cycEGFP partially rescues cyc01

        (Liu et al., 2015)
        Comments

        cycT:Avic\GFP-EGFP significantly rescues circadian rhythms (84% of flies show rhythmicity with a 25.9hr period) in cyc01/cyc01 flies under dark conditions.

        (Liu et al., 2015)
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        cycEGFP
        cycT:Avic\GFP-EGFP
        Name Synonyms
        Secondary FlyBase IDs
          References (1)