kirrerP298 zygotic mutant embryos exhibit myoblast fusion defects. In contrast to the round and dense morphology seen in wild type, the F-actin enriched-structures between unfused fusion-competent myoblasts and miniature myotubes are irregularly shaped and exhibit abnormally long protrusions.
kirrerP298-G4 has myoblast phenotype, enhanceable by Rho172O
kirrerP298-G4 has myoblast phenotype, enhanceable by zip1
Rho172O, kirrerP298-G4 has myoblast phenotype, suppressible | partially by sqhE21.Tag:FLAG
Rho172O enhances the myoblast fusion defects seen in kirrerP298 mutant embryos.
zip1 enhances the myoblast fusion defects seen in kirrerP298 mutant embryos. In contrast to the round and dense morphology seen in wild type, the F-actin enriched-structures between unfused fusion-competent myoblasts and miniature myotubes are irregularly shaped and exhibit abnormally long protrusions.
Expression of sqhE21.T:Zzzz\FLAG partially suppresses the myoblast fusion defects seen in kirrerP298 Rho172O mutant embryos, returning fusion to the level of kirrerP298 mutants alone.
