FB2024_03 , released June 25, 2024
Allele: Dmel\MarfF
Open Close
General Information
Symbol
Dmel\MarfF
Species
D. melanogaster
Name
FlyBase ID
FBal0299662
Feature type
allele
Associated gene
Dmel\Marf
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Sandoval et al., 2014)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:6,369,869..6,369,869 [+]
Nucleotide change:

T6369869C

Amino acid change:

L704P | Marf-PB; L704P | Marf-PC; L708P | Marf-PD

Reported amino acid change:

L708P

Comment:

Site of reported amino acid change is relative to Marf-PD. Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Sandoval, 2015.5.4)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die as third instar larvae after an extended larval period of 18-21 days.

      Homozygous clones in the eye result in electroretinogram defects, including a reduction in amplitude.

      (Sandoval et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      MarfF is rescued by MarfTag:HA

      (Sandoval et al., 2014)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      MarfF
      (Sandoval, 2015.5.4, Sandoval et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)