FB2024_03 , released June 25, 2024
Allele: Dmel\ADD12
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General Information
Symbol
Dmel\ADD12
Species
D. melanogaster
Name
FlyBase ID
FBal0297272
Feature type
allele
Associated gene
Dmel\ADD1
Associated Insertion(s)
Carried in Construct
Also Known As
dadd12
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Alekseyenko et al., 2014)
Mutagen
P-element activity
(Alekseyenko et al., 2014)
Progenitor genotype
P{GawB}ADD1NP0793
(Alekseyenko et al., 2014)
Cytology
Description

Imprecise excision of P{GawB}ADD1NP0793 resulting in deletion of 2R:7 ,857,967 - 2R:7 ,862,584 bp (FB2012_06 coordinates).

(Alekseyenko et al., 2014)

Deletion that eliminates most of the coding region of ADD1 without affecting the neighbouring gene.

(Alekseyenko et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:11,970,462..11,975,079 [+]
Comment:

A deletion resulting from the imprecise excision of P{GawB}ADD1NP0793 was mapped to release 5 genome coordinates 2R:7 ,857,967..7,862,584.

(Alekseyenko et al., 2014, Alekseyenko et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A dominant suppressor of variegation effect of ADD12 is observed in the In(1)wm4/Y background, which is stronger in homozygotes or ADD12/Df(2R)BSC153 trans-heterozygotes.

      (Alekseyenko et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      ADD12
      CG82902
      cg82902
      (Alekseyenko et al., 2014, Alekseyenko et al., 2014)
      dadd12
      (Meyer-Nava et al., 2020, Chavez et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)