FB2024_03 , released June 25, 2024
Allele: Dmel\sensm1
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General Information
Symbol
Dmel\sensm1
Species
D. melanogaster
Name
FlyBase ID
FBal0295889
Feature type
allele
Associated gene
Dmel\sens
Associated Insertion(s)
Carried in Construct
PBac{sens-m1}
Key Links
Transgenic product class
genomic_DNA
(Cassidy et al., 2013)
wild_type
(Cassidy et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Cassidy et al., 2013)
wild_type
(Cassidy et al., 2013)
Mutagen
in vitro construct
(Cassidy et al., 2013)
Progenitor genotype
sens+t18.1
(Cassidy et al., 2013)
Carried in construct
PBac{sens-m1}
Cytology
Description

Mutation of one of the two predicted mir-9a binding sites present in the sens 3'UTR.

(Cassidy et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
sens
Encoded product / tool
sens
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing two copies of sensm1 in a sensE1 background show increased variability in scutellar bristle number compared to controls.

      (Cassidy et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      sensE1/sensm1 is an enhancer of scutellar bristle | heat sensitive phenotype of sc1

      (Cassidy et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Heterozygosity for mir-9aunspecified results in an increase in mean scutellar bristle number (compared to individuals carrying two wild-type copies of mir-9a) in individuals carrying two copies of sensm1.

      Flies carrying sensm1 in a sensE1 background show enhanced temperature dependence of the scutellar bristle phenotype (loss of scutellar bristles) of sc1 flies compared to controls carrying sens+t18.1 in a sc1 sensE1 background.

      (Cassidy et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sensm1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)